Publications by authors named "Xi-Bin Lu"
Eu isotopes are promising tracers across various scientific domains such as planetary, earth, and marine science, yet their high-precision analysis has been challenging due to the similar geochemical properties of rare earth elements (REEs). In this study, a novel two-column chromatographic approach was developed utilizing AG50W-X12 and TODGA resins to separate Eu effectively from matrix and interfering elements like Ba, Nd, Sm, and Gd, while ensuring high Eu yields (99.4 ± 0.
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- Cytokines play a crucial role in immunotherapy but face challenges like short lifespan and side effects, prompting the development of a portable smart blue-light controlled (PSLC) device.
- This PSLC device uses optogenetic technology to regulate cytokine expression specifically in tumors when triggered by blue light.
- The approach successfully enhances immune cell activity against tumors, overcoming immunosuppression and leading to significant tumor shrinkage in mice, presenting a promising new strategy for cytokine therapy in immunotherapy research.
Synthetic biology circuits are often constructed with multiple gene expression units assembled in close proximity, and they can be used to perform complex functions in embryonic stem cells (ESCs). However, mutual interference between transcriptional units has not been well studied in mouse ESCs. To assess the efficiency of insulators at suppressing promoter interference in mouse ESCs, we used an evaluation scheme in which a tunable tetracycline response element promoter is connected to a constant Nanog promoter.
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