Effect of powder combined with conventional therapy on mild to moderate fatty liver.

Background: Nonalcoholic fatty liver disease (NAFLD) encompasses a variety of liver conditions impacting individuals who consume minimal or no alcohol. Recently, traditional Chinese medicine has been gradually used to treat mild to moderate fatty liver, among which Lindl. powder has been affirmed by many doctors and patients to be effective.

Influence of pH on the Formation of Benzyl Ester Bonds Between Dehydrogenation Polymers and Konjac Glucomannan.

A thorough understanding of the lignin-carbohydrate complex (LCC) structure has a significant meaning in the high-value utilization of lignocellulose. In this work, the complex (DHPKGC) was obtained by an addition reaction between konjac glucomannan (KGM) and quinone methides generated in the synthesis of dehydrogenation polymers (DHPs) to simulate the formation of LCCs. The effect of pH on the prepared DHPKGC was investigated.

Comparison of dexmedetomidine with midazolam for third molar surgery: A meta-analysis of randomized controlled trials.

Introduction: The analgesic sedation of dexmedetomidine compared with midazolam for third molar surgery remains controversial. We conduct a systematic review and meta-analysis to explore the influence of dexmedetomidine versus midazolam for third molar surgery.

Methods: We have searched PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through December 2022 for randomized controlled trials assessing the effect of dexmedetomidine versus midazolam for third molar surgery.

MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.

Background: Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a common cause of end-stage renal disease (ESRD). Mesenchymal stem cells (MSCs) possess potent anti-inflammatory and immunomodulatory properties, which render them an attractive therapeutic tool for tissue damage and inflammation.

Methods: This study was designed to determine the protective effects and underlying mechanisms of human umbilical cord-derived MSCs (UC-MSCs) on streptozotocin-induced DN.

Isolation and Fractionation of the Tobacco Stalk Lignin for Customized Value-Added Utilization.

The value-added utilization of tobacco stalk lignin is the key to the development of tobacco stalk resources. However, the serious heterogeneity is the bottleneck for making full use of tobacco stalk lignin. Based on this, lignin was separated from tobacco stalk through hydrothermal assisted dilute alkali pretreatment.

Adsorption of Ni in aqueous solution by KMnO modified biomass: investigation on adsorption kinetics and modification mechanism.

In this study, KMnO modification was proved to effectively increase the Ni adsorption capacity of biomass. In order to clarify the KMnO modification mechanism, the Ni adsorption characteristics of KMnO modified corncob (PPCB) under adsorption time, pH and Ni concentration were studied. The results showed that the adsorption was the pseudo second-order kinetic process, indicating that chemisorption was the dominated process, which followed the Langmuir isotherm model and the highest Ni adsorption capacity of PPCB reached 35.

Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signaling.

As a major producer of the inflammatory cytokine interleukin-1 (IL-1), peripheral macrophages can augment IL-1 expression via type 1 IL-1 receptor (IL-1R1) mediated autocrine self-amplification. In the CNS, microglial cells are the major producers of inflammatory cytokines, but express negligible levels of IL-1R1. In the present study, we showed CNS IL-1 induced microglial proinflammatory cytokine expression was mediated by endothelial, not microglial, IL-1R1.

How do taxonomic versus thematic relations impact similarity and difference judgments? An ERP study.

Taxonomically related concepts like "bee" and "butterfly" and thematically related concepts like "bee" and "honey" have different roles in similarity judgments. We examined the complex impact of taxonomic and thematic relations on similarity and difference judgments via ERPs in a S1-S2 paradigm. Subjects were required to remember a word denoting some object or animal (S1), and compare that to a second word (S2) that was either thematically related, taxonomically related or unrelated to S1, making a "high" or "low" similarity and difference judgments in separate blocks.

Dissociating the effects of habituation, black walls, buspirone and ethanol on anxiety-like behavioral responses in shoaling zebrafish. A 3D approach to social behavior.

Understanding the different patterns of anxiety-like behavioral responses is of great interest for pharmacological and genetic research. Here we report the effects of 3.5-hr habituation, buspirone and ethanol on those responses in shoaling zebrafish (Danio rerio).