Tension-Tension Fatigue Behavior of High-Toughness ZrTiCuAl Bulk Metallic Glass.

Bulk metallic glasses have application potential in engineering structures due to their exceptional strength and fracture toughness. Their fatigue resistance is very important for the application as well. We report the tension-tension fatigue damage behavior of a ZrTiCuAl bulk metallic glass, which has the highest fracture toughness among BMGs.

Efficacy of Dexamethasone for Reducing Edema and Ecchymosis After Rhinoplasty: A Systematic Review and Meta-analysis.

Background: Rhinoplasty is one of the most challenging cosmetic surgical operations. The procedure has been known to precipitate higher levels of edema and ecchymosis in the periorbital and paranasal regions. The literature recommends the use of corticosteroids such as dexamethasone to alleviate these postoperative morbidities.

Edaravone reduces oxidative stress and intestinal cell apoptosis after burn through up-regulating miR-320 expression.

Background: Intestinal mucosa barrier dysfunction after burn injury is an important factor for causing mortality of burn patients. The current study established a burn model in rats and used a free radical scavenger edaravone (ED) to treat the rats, so as to investigate the effect of edaravone on intestinal mucosa barrier after burn injury.

Methods: Anesthetized rats were subjected to 40% total body surface area water burn immediately, followed by treatment with ED, scrambled antagomir, or antagomiR-320.

[Effects of oxymatrine on the expressions of pro-collagen and fibronectin of fibroblasts derived from human hyperplastic scars].

Objective: To study the effects of oxymatrine (OM) on the expressions of pro-collagen I (PC I), pro-collagen II (PC III), fibronectin (FN), matrix metalloproteinase-1 (MMP-1) mRNA of fibroblasts from keloid (KFb), hyperplastic scar (HFb), and normal skin (NFb), and to compare with hydrocortisone (HC).

Methods: The primary KFb, HFb and NFb were derived from patients and cultured in vitro using tissue block culture method. The fibroblasts were treated with 500 microg/mL OM, 2 microg/mL HC, or without any medicine (as the control).

[Effect of periostin on the function of human umbilical vein endothelial cells in acidic environment].

Objective: To observe the effect of recombinant periostin protein on the proliferation, apoptosis and migration of human umbilical vein endothelial cells (HUVECs) in acidic environment.

Methods: HUVECs were divided into three groups: normal control (pH 7.31±0.