Background: There are few studies on the locus coeruleus (LC) in frontotemporal lobar degeneration (FTLD) and the potential differences in the LC related to the underlying proteinopathy.
Objective: The aim of this study was to investigate the LC in FTLD subgroups.
Methods: Neuropathological cases diagnosed with FTLD were included.
A wide range of neurological manifestations have been associated with the development of COVID-19 following SARS-CoV-2 infection. However, the etiology of the neurological symptomatology is still largely unexplored. Here, we used state-of-the-art multiplexed immunostaining of human brains ( = 6 COVID-19, median age = 69.
View Article and Find Full Text PDFRev Esp Cardiol (Engl Ed)
February 2018
The preferred management of a cardiac mass remains controversial, but it often includes open-chest surgical excision to obtain an adequate tissue sample for histological workup. We herein report a less invasive approach in which an accurate and timely cytological diagnosis of pericardial angiosarcoma was reached by studying a CT-guided fine-needle aspiration cell block. The cell block showed proliferation of atypical cells with occasional mitotic figures, vasoformative features, and immunoreactivity to WT1, vimentin, CD31, CD34, ERG, and Ki67.
View Article and Find Full Text PDFBackground And Objective: Secondary amyloidosis (AA) is a rare complication of rheumatic diseases.
Objective: The aim of this study was to determine the frequency of symptomatic amyloidosis AA in patients with spondyloarthropathy.
Patients And Method: Retrospective study (1984-2013).