Publications by authors named "Xavier Jimenez-Fabrega"

Purpose: COVID-19 is an independent risk factor for cardiovascular disease. The aim of this study is to determine the burden, characteristics, and causes of sudden death in sport (SrSD) before and after the COVID-19 pandemic in the general population.

Methods: Retrospective observational study.

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Background: Acute ischemic stroke is a leading cause of pediatric death and disability. A clinical scale adapted for children can ensure early detection of candidates for urgent acute ischemic stroke treatment. The Rapid Arterial Occlusion Evaluation (RACE) scale for adults, which scores 5 items (facial palsy 0-2; arm motor function 0-2; leg motor function 0-2; head/gaze deviation 0-1; and aphasia or agnosia 0-2), has good sensitivity and specificity in detecting large vessel occlusion.

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Article Synopsis
  • The study investigates the relationship between CPR practices and ribcage injuries, identifying key risk factors contributing to severe damage during resuscitation.
  • Data were gathered from 200 out-of-hospital CPR attempts, revealing that a significant 65% of patients suffered serious ribcage injuries, with age and cardiac mass ratio as major influencing factors.
  • The findings suggest that understanding the heart's role in CPR biomechanics is crucial, highlighting the importance of cardiac mass ratio as a significant risk factor for injuries during CPR.
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Objectives: To study prehospital care process in relation to hospital outcomes in stroke-code cases first attended by 2 different levels of ambulance. To analyze factors associated with a satisfactory functional outcome at 3 months.

Material And Methods: Prospective multicenter observational cohort study.

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Objective: The objective of this study was to develop and validate a risk scale (MARIACHI) for patients classified as non-ST-segment elevation acute coronary syndrome (NSTEACS) in a prehospital setting with the ability to identify patients at an increased risk of mortality at an early stage.

Methods: A retrospective observational study conducted in Catalonia over two periods: 2015-2017 (development and internal validation cohort) and Aug 2018-Jan 2019 (external validation cohort). We included patients classified as prehospital NSTEACS, assisted by an advanced life support unit and requiring hospital admission.

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Article Synopsis
  • The study examines the impact of different types of first medical contact (FMC), such as EMS, community hospital, PCI hospital, and primary care center, on mortality rates in STEMI patients undergoing primary coronary intervention between 2010-2020.
  • Out of 18,332 patients, those who received care at PCI hospitals and community hospitals showed higher 1-year mortality rates, while patients at primary care centers had better outcomes despite longer delays in treatment.
  • The findings suggest that receiving first medical assistance from PCI and community hospitals may lead to worse survival rates compared to emergency medical services, while primary care centers presented a lower risk and better results overall.
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Background: We analyzed the main factors associated with intravenous thrombolysis (IVT) in patients with minor ischemic stroke.

Methods: Data were obtained from a prospective, government-mandated, population-based registry of stroke code patients in Catalonia (6 Comprehensive Stroke Centers, 8 Primary Stroke Centers, and 14 TeleStroke Centers). We selected patients diagnosed with ischemic stroke and National Institutes of Health Stroke Scale (NIHSS) ≤5 at hospital admission from January 2016 to December 2020.

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Objectives: To examine gender-related differences in the management and survival of out-of-hospital cardiac arrest (OHCA) in Spain during 2 time series.

Material And Methods: Analysis of data recorded in the prospective Spanish OHCA registry (OHSCAR in its Spanish acronym) for 2 time series (2013-2014 and 2017-2018). We included all 11 036 consecutive cases in which an emergency team intervened.

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Background: The extraordinary situation caused by the onset of COVID-19 has meant that at prehospital level, the number of treatments, profile and time taken to respond for treating time-dependent pathologies has been greatly affected. However, it is not known whether the prehospital profile of polytrauma patients (PTP) has been affected.

Objective: To determine differences in the epidemiological characteristics and the clinical variables of prehospital polytrauma patients during the first wave of the COVID-19 pandemic in Catalonia.

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Article Synopsis
  • The COVID-19 pandemic significantly disrupted acute stroke care in Catalonia, with a 22% decrease in stroke code activations and a 29% drop in reperfusion therapies compared to the prepandemic period.
  • Delays in emergency medical services (EMS) response times increased by 42 minutes, and the time from stroke onset to hospital arrival grew by 53 minutes, suggesting a strong correlation between rising COVID-19 cases and slower emergency responses.
  • As a result, there was an increase in mortality rates (with a 60% higher odds of death) and a decrease in favorable clinical outcomes within 90 days post-stroke during the pandemic.
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Objectives: The need for primary percutaneous coronary intervention in hospitals without hemodynamic support capability is associated with delays between first medical contact (FMC) and reperfusion. It is important to identify factors involved in delays, particularly if they are relevant to the organization of emergency services.

Material And Methods: Analysis of a registry of patients treated in hospitals without advanced hemodynamic support systems in a catchment area with an established care network for acute ST-segment elevation myocardial infarction (STEMI).

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Remote ischemic perconditioning during cerebral ischemia (RIPerC) refers to the application of brief episodes of transient limb ischemia commonly to a limb, it represents a new safe, simple and low-cost paradigm in neuroprotection. To evaluate the effects of RIPerC on acute ischemic stroke (AIS) patients, applied in the ambulance, to improve functional outcomes compared with standard of care. A sample size of 286 patients in each arm achieves 80% power to detect treatment differences of 14% in the outcome, using a two-sided binomial test at significance level of 0.

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Article Synopsis
  • The study investigates how the COVID-19 pandemic affected out-of-hospital cardiac arrest (OHCA) incidents across Spain, analyzing data from over 8,600 cases before and during the pandemic.
  • Results showed a significant drop in resuscitation attempts and lower survival rates to hospital admission and discharge during the COVID-19 period compared to the non-COVID timeframe.
  • The findings highlight the need to adapt emergency care practices during high-risk infection periods to improve OHCA outcomes.
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Objectives: Process indicators have been widely used to monitor the way trauma care is provided. We aimed to analyze whether data from a hospital's severe trauma register could facilitate the evaluation of aspects of the initial management of severe injuries.

Material And Methods: Observational, retrospective population-based study.

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"Time-dependent" pathologies, understood as those in which diagnostic or therapeutic delay negatively influences the evolution and prognosis of a case, are considered to be critical in emergencies, as their morbidity and mortality is directly related to delay in starting treatment. Examples of this type of pathology can be found in normal clinical practice, i.e.

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Objective: We investigated the results obtained with a basic cardiopulmonary resuscitation (b-CPR) program (PROCES) specifically designed for secondary school students (14-16 years old) and taught by emergency physicians.

Methods: We used a multiple-choice test with 20 questions (10 on theory and 10 on skills) answered before and immediately after and 1 year after receiving the b-CPR course. Satisfactory learning was considered when at least 8 out of 10 skill questions were correctly answered.

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