Usability of OMOP Common Data Model for Detailed Lab Microbiology Results.

Anti-microbial resistance surveillance systems in Europe are limited by the inability to link laboratory data and patient data. The OMOP Common Data Model (OMOP CDM) is an option to store and use patient data in an international context supporting observational research. Detailed medical microbiology laboratory data are usually not stored in OMOP CDM.

SNOMED CT Coding and Analytics of in vitro Diagnostics Observations.

This work investigates the capability of SNOMED CT to encode microbiology laboratory data with the goal of fully describing multidrug resistance and breakpoint assignment by specimen.

Semantic data interoperability, digital medicine, and e-health in infectious disease management: a review.

Disease management requires the use of mixed languages when discussing etiology, diagnosis, treatment, and follow-up. All phases require data management, and, in the optimal case, such data are interdisciplinary and uniform and clear to all those involved. Such semantic data interoperability is one of the technical building blocks that support emerging digital medicine, e-health, and P4-medicine (predictive, preventive, personalized, and participatory).

Regulation of root ion transporters by photosynthesis: functional importance and relation with hexokinase.

Coordination between the activity of ion transport systems in the root and photosynthesis in the shoot is a main feature of the integration of ion uptake in the whole plant. However, the mechanisms that ensure this coordination are largely unknown at the molecular level. Here, we show that the expression of five genes that encode root NO(3)(-), NH(4)(+), and SO(4)(2-) transporters in Arabidopsis is regulated diurnally and stimulated by sugar supply.

The expression of the t-SNARE AtSNAP33 is induced by pathogens and mechanical stimulation.

The fusion of vesicles in the secretory pathway involves the interaction of t-soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) on the target membrane and v-SNAREs on the vesicle membrane. AtSNAP33 is an Arabidopsis homolog of the neuronal t-SNARE SNAP-25 involved in exocytosis and is localized at the cell plate and at the plasma membrane. In this paper, the expression of AtSNAP33 was analyzed after different biotic and abiotic stresses.