Publications by authors named "Xavier Fabre"
Objective: To describe neuroimaging findings and to report the epidemiologic and clinical characteristics of patients with coronavirus disease 2019 (COVID-19) with neurologic manifestations.
Methods: In this retrospective multicenter study (11 hospitals), we included 64 patients with confirmed COVID-19 with neurologic manifestations who underwent a brain MRI.
Results: The cohort included 43 men (67%) and 21 women (33%); their median age was 66 (range 20-92) years.
Article Synopsis
- Background: The study examines brain MRI abnormalities in patients with severe COVID-19 (SARS-CoV-2) and identifies potential neurological issues related to the virus.
- Methods: Researchers analyzed data from 37 hospitalized patients who had neurological symptoms and abnormal brain MRIs between March and April 2020, excluding cases with ischemic strokes or unrelated chronic lesions.
- Results: The patient cohort, primarily older men, exhibited various neurological symptoms, with MRI findings showing significant abnormalities in brain regions including the medial temporal lobe and evidence of microhemorrhages, suggesting COVID-19's impact on brain structure.
Article Synopsis
- The study aimed to assess how a visual aid affects the differences in prognosis estimates between physicians and family members in an intensive care setting.
- Conducted in two ICU units, one used a visual aid showing patient progress on a 10-point scale, while the other relied only on verbal information; the prognosis was evaluated on day 7.
- Results showed that discordance in prognosis was significantly lower (31%) with the visual aid compared to the unit with only verbal information (55%), indicating that the visual tool improved agreement between families and doctors.
Differential Perceptions of Noninvasive Ventilation in Intensive Care among Medical Caregivers, Patients, and Their Relatives: A Multicenter Prospective Study-The PARVENIR Study.
Anesthesiology
June 2016
Background: Noninvasive ventilation (NIV) requires a close "partnership" between a conscious patient and the patient's caregivers. Specific perceptions of NIV stakeholders and their impact have been poorly described to date. The objectives of this study were to compare the perceptions of NIV by intensive care unit (ICU) physicians, nurses, patients, and their relatives and to explore factors associated with caregivers' willingness to administer NIV and patients' and relatives' anxiety in relation to NIV.
View Article and Find Full Text PDFPurpose: Noninvasive ventilation (NIV) is a treatment option in patients with acute respiratory failure who are good candidates for intensive care but have declined tracheal intubation. The aim of our study was to report outcomes after NIV in patients with a do-not-intubate (DNI) order.
Methods: Prospective observational cohort study in all patients who received NIV for acute respiratory failure in 54 ICUs in France and Belgium, in 2010/2011.
Background: This clinical study evaluated the effect of a suctioning maneuver on aspiration past the cuff during mechanical ventilation.
Methods: Patients intubated for less than 48 hours with a PVC-cuffed tracheal tube, under mechanical ventilation with a PEEP ≥5 cm H2O and under continuous sedation, were included in the study. At baseline the cuff pressure was set at 30 cm H2O.