Publications by authors named "Xavier Andrade-Gonzalez"

Article Synopsis
  • The study examined the effectiveness of routine pre-emptive COVID-19 screening in cancer patients before treatment, comparing outcomes between those screened routinely and those diagnosed based on symptoms or exposure.
  • A total of 5,452 patients underwent routine screening, with only 44 diagnosed with COVID-19, leading to similar hospitalization and mortality rates as those diagnosed based on clinical suspicion.
  • The findings suggest that routine screening for asymptomatic cancer patients doesn't significantly improve outcomes, indicating its limited value in this context.
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Patients with Hodgkin lymphoma (HL) can achieve excellent response and survival rates following frontline combination chemo- and radiation therapy. However, about 10-15% of patients will experience disease relapse which is associated with poor outcomes. Recent breakthroughs in understanding the mechanisms of oncogenicity and interactions within the tumor microenvironment have resulted in development of novel drugs for treatment of patients with HL.

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With recent novel therapies, cancer survival has improved and chemotherapy-induced cardiac toxicity including left ventricular dysfunction and heart failure has a greater potential impact on long-term outcomes. Hence, the prevention of cardiotoxicity should be an important objective when planning the therapy of cancer patients. Different pharmacologic and nonpharmacologic approaches have been shown to be effective in small trials, most of them in patients treated with anthracyclines.

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