GPR68 Is a Neuroprotective Proton Receptor in Brain Ischemia.

Background And Purpose: Brain acidosis is prevalent in stroke and other neurological diseases. Acidosis can have paradoxical injurious and protective effects. The purpose of this study is to determine whether a proton receptor exists in neurons to counteract acidosis-induced injury.

Infection-induced endothelial amyloids impair memory.

Patients with nosocomial pneumonia exhibit elevated levels of neurotoxic amyloid and tau proteins in the cerebrospinal fluid (CSF). studies indicate that pulmonary endothelium infected with clinical isolates of either , , or produces and releases cytotoxic amyloid and tau proteins. However, the effects of the pulmonary endothelium-derived amyloid and tau proteins on brain function have not been elucidated.

Human ASIC1a mediates stronger acid-induced responses as compared with mouse ASIC1a.

Acid-sensing ion channels (ASICs) are the major proton receptor in the brain and a key mediator of acidosis-induced neuronal injuries in disease. Most of published data on ASIC function came from studies performed in mice, and relatively little is known about potential differences between human and mouse ASICs (hASIC and mASIC, respectively). This information is critical for us to better interpret the functional importance of ASICs in human disease.

[Net carbon exchange and its environmental affecting factors in a forest plantation in Badaling, Beijing of China].

By using eddy covariance technique, a year-round (November, 2011-October, 2012) continuous measurement of net ecosystem carbon dioxide exchange (NEE) was conducted in a 4-year old mixed forest plantation in Badaling of Beijing. The forest plantation ecosystem was a net carbon sink in July and August, but a carbon source in the rest months. The monthly net carbon loss and uptake were the largest in April and July, respectively.

[Macrozoobenthos community structure and its indicative significance in water quality bioassessment of Fenshuijiang Reservoir, Zhejiang Province of East China].

A monthly investigation was conducted on the macrozoobenthos at 7 stations of Fenshuijiang Reservoir in Zhejiang Province of East China from November 2008 to October 2009. A total of 37 taxa were collected, most of which belonged to Oligocheata and Chironomidae. Limnodrilus hoffmeisteri was dominant in spring, summer and autumn, and Chironomus gr.