Publications by authors named "X-K Liu"

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  • Cardiac ischemia/reperfusion (I/R) injury is a significant concern for heart disease, but there's currently no effective treatment to minimize this type of heart damage.
  • This study recruited patients with acute myocardial infarction to examine the impact of plasma RIPK3 levels before and after treatment, using both patient data and lab experiments on cells and mouse models.
  • Elevated RIPK3 levels post-treatment were linked to worse outcomes, and experiments showed that RIPK3 worsens heart injury by triggering inflammation, suggesting its role as a damaging molecule that could be targeted for therapy.
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  • Researchers developed Bi-doped Ti/Sb-SnO/PbO electrode materials through electrodeposition to enhance their efficiency in zinc electrowinning, analyzing their properties using various characterization techniques like SEM, EDS, and XRD.* -
  • The study revealed that the Ti/Sb-SnO/2Bi-PbO electrode had the best hydrophilicity (contact angle of 21.6°), longest lifespan (1196 hours), and superior oxygen evolution activity compared to other electrodes.* -
  • Computational models indicated that Bi doping improves the electrode's catalytic activity and conductivity, making it a promising candidate for energy-efficient zinc electrowinning processes.*
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The article "Fas/FasL induces myocardial cell apoptosis in myocardial ischemia-reperfusion rat model", by X.-M. Liu, Z.

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Objectives: To investigate the mediating role of the activation degree of arginine-proline metabolism in the association of coal dust and decreased lung function.

Methods: Cumulative dust exposure (CDE) represented coal dust exposure, whereas the hydroxyproline-to-arginine concentration ratio (Hyp/Arg) in bronchoalveolar lavage fluid gauged arginine-proline metabolism activation. Pulmonary function indicators, including predicted value of forced vital capacity (FVC%pred), forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC%), and the ratio of actual to predicted value of FEV1 (FEV1%pred), diffusing capacity of the lungs for carbon monoxide (DLCO%pred), difference value between alveolar air and arterial partial oxygen pressure (P (A-a) O 2 ), and 6-minute walking distance test (6MWT), were assessed.

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In this paper, a wide-band, low-profile antenna is presented for a high-integration phased array system. The proposed antenna, implemented using a tightly coupled array, operates over roughly the X-K frequency band and is performant at 8 GHz-18.5 GHz.

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This scoping review aims to investigate longitudinal changes in minerals and vitamins concentrations in human milk among the Chinese population. Following the PRISMA-ScR guidelines, a comprehensive and systematic literature search was conducted using both English and Chinese databases. Data were extracted and categorized into six defined lactation stages.

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Background: The risk of second tumors after chimeric antigen receptor (CAR) T-cell therapy, especially the risk of T-cell neoplasms related to viral vector integration, is an emerging concern.

Methods: We reviewed our clinical experience with adoptive cellular CAR T-cell therapy at our institution since 2016 and ascertained the occurrence of second tumors. In one case of secondary T-cell lymphoma, a broad array of molecular, genetic, and cellular techniques were used to interrogate the tumor, the CAR T cells, and the normal hematopoietic cells in the patient.

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Deep compressive sensing (CS) has become a prevalent technique for image acquisition and reconstruction. However, existing deep learning (DL)-based CS methods often encounter challenges such as block artifacts and information loss during iterative reconstruction, particularly at low sampling rates, resulting in a reduction of reconstructed details. To address these issues, we propose NesTD-Net, an unfolding-based architecture inspired by the NESTA algorithm, designed for image CS.

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Peptide-based hydrogels have great potential for applications in tissue engineering, drug delivery, and so on. We systematically synthesize, characterize, and investigate the self-assembly behaviors of a series of polypeptide-based penta-block copolymers by varying block sequences and lengths. The copolymers contain hydrophobic blocks of poly(γ-benzyl-l-glutamate) (PBG, B) and two kinds of hydrophilic blocks, poly(l-lysine) (PLL, K) and poly(ethylene glycol) (PEG, EG), where and are the number of repeating units of each block, where PBG and PLL blocks have unique functions for nerve regeneration and cell adhesion.

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Background: It is uncertain whether adjunctive thrombolysis is beneficial for patients with ST-segment-elevation myocardial infarction undergoing percutaneous coronary intervention (PCI) within 120 minutes of presentation. This study was to determine whether in patients presenting with ST-segment-elevation myocardial infarction a single bolus recombinant staphylokinase (r-SAK) before timely PCI leads to improved patency of the infarct-related artery and reduces the infarct size.

Methods: This is an open-label, prospective, multicenter, randomized study.

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Aims: A therapeutic strategy for chronic heart failure (HF) is to lower resting heart rate (HR). Ivabradine is a well-known HR-lowering agent, but limited prospective data exist regarding its use in Chinese patients. This study aimed to evaluate the effectiveness and safety of ivabradine in Chinese patients with chronic HF.

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Longyan City in Fujian Province is one of China's top-quality tobacco-producing areas and plays an essential role in local economic development. To determine the correlation between heavy metal content in tobacco leaves and soil factors, soil physical and chemical properties and heavy metal contents of lead, cadmium, and copper in tobacco leaves were measured and analyzed by the correlation regression method. The content of lead, cadmium, and copper in soil was determined using hydrochloric acid extraction-AAS and graphite furnace atomic absorption spectrometry.

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Background: A better understanding of the molecular mechanism of aortic valve development and bicuspid aortic valve (BAV) formation would significantly improve and optimize the therapeutic strategy for BAV treatment. Over the past decade, the genes involved in aortic valve development and BAV formation have been increasingly recognized. On the other hand, (a disintegrin and metalloproteinase with thrombospondin motifs) gene family members have been reported to be able to modulate cardiovascular development and diseases.

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Article Synopsis
  • The study aimed to assess how well quantitative measurements from contrast-enhanced CT scans can differentiate small clear cell renal cell carcinoma (ccRCC) from benign renal tumors like fat-poor angiomyolipoma (fpAML) and renal oncocytoma (RO).
  • A total of 244 patients were analyzed, and various CT scan parameters were measured across different phases, with findings suggesting that specific parameters, especially related to the unenhanced phase (UP), were effective in distinguishing ccRCC from benign tumors.
  • The model incorporating multiple parameters showed significantly higher accuracy and sensitivity compared to radiologists' assessments, indicating that quantitative measurements could enhance diagnostic capabilities in clinical practice.
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The process e^{+}e^{-}→D_{s}^{*+}D_{s}^{*-} is studied with a semi-inclusive method using data samples at center-of-mass energies from threshold to 4.95 GeV collected with the BESIII detector operating at the Beijing Electron Positron Collider. The Born cross sections of the process are measured for the first time with high precision in this energy region.

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Epstein-Barr virus (EBV) is associated with various malignancies and infects >90% of the global population. EBV latent proteins are expressed in numerous EBV-associated cancers and contribute to carcinogenesis, making them critical therapeutic targets for these cancers. Thus, this study aims to develop mRNA-based therapeutic vaccines that express the T-cell-epitope-rich domain of truncated latent proteins of EBV, including truncatedlatent membrane protein 2A (Trunc-LMP2A), truncated EBV nuclear antigen 1 (Trunc-EBNA1), and Trunc-EBNA3A.

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Oxide semiconductors with mixed-valence states generally exhibit excellent optoelectronic and photochemical properties due to facile charge transfer in redox reactions. In this work, we investigate the effects of mixed alkali on the optical absorption, luminescence spectra and photocatalytic abilities of (NaK)SbO nanoparticles. All the samples are fabricated using a simple one-step hydrothermal method.

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Background: Currently, noninvasive arteriography for the diagnosis of coronary artery disease is clinically limited to the computed tomography scanning, where patients have to be exposed to the radiation and risks associated with iodinated contrast. We aimed to investigate the diagnostic performance and safety of a novel ferumoxytol-enhanced coronary magnetic resonance angiography (CMRA) in patients with suspected coronary artery disease.

Methods: Thirty patients, 19 males, with a median age of 63 years old, and 17 with renal insufficiency, who were scheduled for invasive coronary angiography, were enrolled.

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  • A study investigated the effectiveness and safety of acupuncture, doxylamine-pyridoxine, and their combination for treating moderate to severe nausea and vomiting during pregnancy (NVP) in 352 early-pregnancy women across 13 hospitals in China from mid-2020 to early 2022.
  • Results showed that all treatment groups (acupuncture, doxylamine-pyridoxine, and the combination) significantly reduced nausea scores compared to controls, with the combination being the most effective.
  • However, the treatment with doxylamine-pyridoxine was associated with a higher risk of having babies who were small for their gestational age, and the true clinical significance of these findings remains unclear
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Direct seawater electrolysis is promising for sustainable hydrogen gas (H) production. However, the chloride ions in seawater lead to side reactions and corrosion, which result in a low efficiency and poor stability of the electrocatalyst and hinder the use of seawater electrolysis technology. Here we report a corrosion-resistant RuMoNi electrocatalyst, in which the in situ-formed molybdate ions on its surface repel chloride ions.

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Background Quantitative T1, T2, and T2* measurements of carotid atherosclerotic plaque are important in evaluating plaque vulnerability and monitoring its progression. Purpose To develop a sequence to simultaneously quantify T1, T2, and T2* of carotid plaque. Materials and Methods The simultaneous T1, T2, and T2* mapping of carotid plaque (SIMPLE*) sequence is composed of three modules with different T2 preparation pulses, inversion-recovery pulses, and acquisition schemas.

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Background Currently, the hepatic venous pressure gradient (HVPG) remains the reference standard for diagnosis of clinically significant portal hypertension (CSPH) but is limited by its invasiveness and availability. Purpose To investigate a vascular geometric model for noninvasive diagnosis of CSPH (HVPG ≥10 mm Hg) in patients with liver cirrhosis for both contrast-enhanced CT and MRI. Materials and Methods In this retrospective study, consecutive patients with liver cirrhosis who underwent HVPG measurement from August 2016 to April 2019 were included.

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The immunity of patients who recover from coronavirus disease 2019 (COVID-19) could be long lasting but persist at a lower level. Thus, recovered patients still need to be vaccinated to prevent reinfection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or its mutated variants. Here, we report that the inactivated COVID-19 vaccine can stimulate immunity in recovered patients to maintain high levels of anti-receptor-binding domain (RBD) and anti-nucleocapsid protein (NP) antibody titers within 9 months, and high neutralizing activity against the prototype, Delta, and Omicron strains was observed.

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Background: Hematopoietic stem cell (HSC) therapy has shown promise for tissue regeneration after ischemia. Therefore, there is a need to understand mechanisms underlying endogenous HSCs activation in response to ischemic stress and coordination of angiogenesis and repair. SHP-1 plays important roles in HSC quiescence and differentiation by regulation of TGF-β1 signaling.

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is a famous living fossil that plays a significant role in the evolutionary studies of the plant kingdom. To explore the adaptive evolution of the ancient genus Isoetes from China, we focused on (Q.F.

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