B, N Codoped Defective Reduced Graphene Oxide as a Highly Efficient Frustrated Lewis Pairs Catalyst for the Selective Hydrogenation of α,β-Unsaturated Aldehydes to Unsaturated Alcohols.

The development of all-solid-state frustrated Lewis pairs (FLPs) metal-free hydrogenation catalysts with excellent activity and stability remains a significant challenge. In this work, B, N codoped FLPs catalysts (De-rGO-NB) were prepared by the strategy of fabricating carbon defects and heteroatom doping on the surface of reduced graphene oxide and applied in the selective hydrogenation of α,β-unsaturated aldehydes to unsaturated alcohols. It was found that electron-rich pyridine-N (Lewis base) and adjacent electron-deficient B-N (Lewis acid) sites could be constructed on the surface of reduced graphene oxide using dicyandiamide and metaboric acid as N and B sources, thus forming FLPs sites.

Intravenous Alteplase Versus Best Medical Therapy for Patients With Minor Stroke: A Systematic Review and Meta-Analysis.

Background: The efficacy of thrombolysis (IVT) in minor stroke (National Institutes of Health Stroke Scale score, 0-5) remains inconclusive. The aim of this study is to compare the effectiveness and safety of IVT with best medical therapy (BMT) by means of a systematic review and meta-analysis of randomized controlled trials and observational studies.

Methods: We searched the PubMed, Embase, Cochrane Library, and Web of Science databases to obtain articles related to IVT in minor stroke from inception until August 10, 2023.

Phytochemical consumption and the risk of teratozoospermia: findings from a hospital-based case-control study in China.

Study Question: Are dietary phytochemicals associated with the risk of teratozoospermia?

Summary Answer: Dietary intake of carotene, including total carotene, α-carotene, β-carotene as well as retinol equivalent, and lutein + zeaxanthin, were inversely correlated with the risk of teratozoospermia.

What Is Known Already: Phytochemicals are natural plant derived bioactive compounds, which have been reported to be potentially associated with male reproductive health. To date, no study has investigated the association between phytochemical intake and the risk of teratozoospermia.

Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2.

Advanced mRNA vaccines play vital roles against SARS-CoV-2. However, most current mRNA delivery platforms need to be stored at -20 °C or -70 °C due to their poor stability, which severely restricts their availability. Herein, we develop a lyophilization technique to prepare SARS-CoV-2 mRNA-lipid nanoparticle vaccines with long-term thermostability.

Ivy Sign in Moyamoya Disease: A Comparative Study of the FLAIR Vascular Hyperintensity Sign Against Contrast-Enhanced MRI.

Background And Purpose: The ability of the ivy sign on contrast-enhanced T1-weighted MR imaging (CEMR) to reflect cerebral perfusion and postoperative revascularization in Moyamoya disease remains largely unknown. We aimed to compare the capabilities of CEMR and FLAIR.

Materials And Methods: CEMR, FLAIR, arterial spin-labeling, and DSA were performed in 44 patients with Moyamoya disease.

Magnetic anisotropy in square pyramidal cobalt(II) complexes supported by a tetraazo macrocyclic ligand.

Two five-coordinate mononuclear Co(ii) complexes [Co(12-TMC)X][B(C6H5)4] (L = 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane (12-TMC), X = Cl- (1), Br- (2)) have been studied by X-ray single crystallography, magnetic measurements, high-frequency and -field EPR (HF-EPR) spectroscopy and theoretical calculations. Both complexes have a distorted square pyramidal geometry with the Co(ii) ion lying above the basal plane constrained by the rigid tetradentate macrocyclic ligand. In contrast to the reported five-coordinate Co(ii) complex [Co(12-TMC)(NCO)][B(C6H5)4] (3) exhibiting easy-axis anisotropy, an easy-plane magnetic anisotropy was found for 1 and 2via the analyses of the direct-current magnetic data and HF-EPR spectroscopy.

Self-Assembly of Linear Amphiphilic Pentablock Terpolymer PAA-PS-PEO-PS-PAAin Dilute Aqueous Solution.

A series of linear amphiphilic pentablock terpolymer PAA--PS--PEO--PS--PAA (ASOSA) with various lengths of the PAA block ( = 15, 40, 60, and 90) were synthesized via a two-step atom transfer radical polymerization (ATRP) using Br-poly(ethylene oxide)-Br (Br-PEO-Br) as the macroinitiator, styrene (St) as the first monomer, and ert-butyl acrylate (BA) as the second monomer, followed with the hydrolysis of PBA blocks. The ASOSA pentablock terpolymers formed micelles in dilute aqueous solution, of which the morphologies were dependent on the length of the PAA block. Cryogenic transmission electron microscopy (cryo-TEM), dynamic light scattering (DLS), and zeta potential measurement were employed to investigate the morphologies, chain structures, size, and size distribution of the obtained micelles.

3D Black-Blood Luminal Angiography Derived from High-Resolution MR Vessel Wall Imaging in Detecting MCA Stenosis: A Preliminary Study.

Background And Purpose: 3D high-resolution vessel wall imaging is increasingly used for intracranial arterial diseases. This study compared the diagnostic performance of black-blood luminal angiography derived from 3D vessel wall imaging with source images of vessel wall imaging and TOF-MRA in detecting middle cerebral artery stenosis.

Materials And Methods: Sixty-two patients with suspected MCA atherosclerosis underwent TOF-MRA, vessel wall imaging, and CTA.

Prehypertension During Normotensive Pregnancy and Postpartum Clustering of Cardiometabolic Risk Factors: A Prospective Cohort Study.

The nonstratification of blood pressure (BP) levels may underestimate future cardiovascular risk in pregnant women who present with BP levels in the range of prehypertension (120-139/80-89 mm Hg). We prospectively evaluated the relationship between multiple antepartum BP measurements (from 11(+0) to 13(+6) weeks' gestation to term) and the occurrence of postpartum metabolic syndrome in 507 normotensive pregnant women after a live birth. By using latent class growth modeling, we identified the following 3 distinctive diastolic BP (DBP) trajectory groups: the low-J-shaped group (34.