CT-Scan-Assessed Body Composition and Its Association with Tumor Protein Expression in Endometrial Cancer: The Role of Muscle and Adiposity Quantities.

: Endometrial cancer is strongly associated with obesity, and tumors often harbor mutations in major cancer signaling pathways. To inform the integration of body composition into targeted therapy paradigms, this hypothesis-generating study explores the association between muscle mass, body fat, and tumor proteomics. : We analyzed data from 113 patients in The Cancer Genome Atlas (TCGA) and Cancer Proteomic Tumor Analysis Consortium (CPTAC) cohorts and their corresponding abdominal CT scans.

Syndromic Retinitis Pigmentosa.

Retinitis pigmentosa (RP) is a progressive inherited retinal dystrophy, characterized by the degeneration of photoreceptors, presenting as a rod-cone dystrophy. Approximately 20-30% of patients with RP also exhibit extra-ocular manifestations in the context of a syndrome. This manuscript discusses the broad spectrum of syndromes associated with RP, pathogenic mechanisms, clinical manifestations, differential diagnoses, clinical management approaches, and future perspectives.

synthesis of gold nanoparticles embedded in a magnetic nanocomposite of glucosamine/alginate for enhancing recyclable catalysis performance of nitrophenol reduction.

In this study, we introduce an synthesis technique for incorporating gold nanoparticles (AuNPs) into a magnetic nanocomposite made of glucosamine and alginate (GluN/Alg) ionotropic gelation. GluN acted as a reducing agent for gold ions, leading to the formation of AuNPs which embedded in the nanocomposite FeO@GluN/Alg. Analytical techniques confirmed the crystallite structure of the nanocomposite AuNPs/FeO@GluN/Alg, which had an average size of 30-40 nm.

Glaucoma Clinic Monitoring Over 6 Months Using Online Circular Contrast Perimetry in Comparison with Standard Automatic Perimetry: The Developing-World Setting.

Purpose: Online circular contrast perimetry provides visual field testing on any computer or tablet without additional hardware. This study compared outcomes of online circular contrast perimetry (OCCP) and standard automated perimetry (SAP) in a developing world setting.

Methods: The longitudinal and observation study was conducted on patients sampled during 2023 at Hanoi Medical University Hospital.

STABLE trial of spectacle provision and driving safety among myopic motorcycle users in Vietnam: study protocol for a stepped-wedge, cluster randomised trial.

Background: Traffic crashes are the leading cause of death globally for people aged 5-29 years, with 90% of mortality occurring in low- and middle-income countries (LMICs). The STABLE (Slashing Two-wheeled Accidents by Leveraging Eyecare) trial was designed to determine whether providing spectacles could reduce risk among young myopic motorcycle users in Vietnam.

Methods: This investigator-masked, stepped-wedge, cluster randomised naturalistic driving trial will recruit 625 students aged 18-23 years, driving ≥ 50 km/week, with ≥ 1-year driving experience and using motorcycles as their primary means of transport, in 25 clusters of 25 students in Ho Chi Minh City, Vietnam.