The study aims to explore how changes in blood flow due to patent ductus arteriosus (PDA) affect white matter damage in premature infants.
Researchers observed 106 premature infants, categorizing them into three groups: those with hemodynamic changes (hsPDA), those without (non-hsPDA), and a control group without PDA.
Findings revealed that infants in the hsPDA group had significantly higher levels of neuron-specific enolase and variations in lateral ventricle gray scale values, indicating a strong link between blood flow in PDA and white matter damage.