CKMT1 deficiency contributes to mitochondrial dysfunction and promotes intestinal epithelial cell apoptosis via reverse electron transfer-derived ROS in colitis.

Mitochondrial dysfunction contributes to the pathogenesis of ulcerative colitis (UC). As a mitochondrial isozyme of creatine kinases, which control energy metabolism, CKMT1 is thought to be a critical molecule in biological processes. However, the specific role of CKMT1 in intestinal inflammation remains largely unknown.

Quality control and spectrum-effect relationship of polysaccharide from different habitats.

The polysaccharides of (CPP) from ten habitats were prepared through water abstraction and alcohol precipitation. Subsequently, an analysis was conducted on their physicochemical properties and molecular structure. The establishment of multidimensional fingerprints is based on instrumental analysis methods.

Solvent Regulation in Layered Zn-MOFs for CH/CO and CO/CH Separation.

The development of alternative adsorptive separation technologies is extremely significant for the separation of CH/CO and CO/CH in the chemical industry. Emerging metal-organic frameworks (MOFs) have shown great potential as adsorbents for gas adsorption and separation. Herein, we synthesized two layered Zn-MOFs, UPC-96 and UPC-97, with 1,2,4,5-tetrakis(4-carboxyphenyl)-3,6-dimethylbenzene (TCPB-Me) as a ligand via the solvent regulation of the pH values.

Primary exploration of cell-free DNA in the plasma of patients with parathyroid neoplasms using next-generation sequencing.

Background And Aims: Plasma cell-free DNA (cfDNA) has been used to monitor gene mutations and diagnose tumors. Discriminating parathyroid carcinoma (PC) from parathyroid adenoma (PA) before surgery is difficult because of the overlap in clinical features between parathyroid neoplasms. We aimed to detect cfDNA mutations in plasma samples from PC and PA patients before surgery to predict the CDC73 status in tumor tissue and help in the differential diagnosis of parathyroid neoplasms.

Characterization of fatty acid desaturase gene family in and their expression patterns in seeds after infection.

Background: The family of membrane-bound fatty acid desaturase () genes play a vital role in plant growth, development, and stress responses. The seed-borne pathogen causes seed decay disease during pre-harvest and post-harvest stages of soybean, leading to a significant reduction in yield and quality. Therefore, it is very meaningful to characterize the diversity and function of the gene family in soybean and to elucidate their roles in seed resistance to

Results: In this study, 30 full-length genes were identified from the soybean genome.