Bioequivalence of two fexofenadine formulations in healthy human volunteers after single oral administration.

Aim: A randomized, two-way, crossover, bioequivalence study was conducted in 25 fasting, healthy, male volunteers to compare two brands of fexofenadine 180 mg tablets, FEXOFENADINE 180 mg Film Tablet (Drogsan A.S., Ankara, Turkey) as test and Telfast 180 mg Tablet (Aventis Pharma, Frankfurt am Main, Germany) as a reference product.

Bioequivalence of two brands of citalopram 40 mg tablets after single oral administration to healthy volunteers.

A randomized, two-way, crossover, bioequivalence study was conducted in 26 fasting, healthy, male volunteers to compare two brands of citalopram 40 mg tablets, Citol (Abdi Ibrahim Ilaç San. ve Tic A.S.

[Determination of pentoxifylline and its major metabolites in human plasma using HPLC].

The present paper describes a rapid, reliable and simple method of pentoxiphyllin in plasma. The worked-out one-step extraction with dichloromethane yields 63% recovery of pentoxiphyllin, 58% recovery of the metabolite and 54% recovery of the internal standard. The employed column with a reverse load of Spherisorb ODS, mobile phase 65% of 0.

[Determination of nifedipine and its metabolites in plasma using gas chromatography].

A method was worked out to determine nifedipine and its metabolite in plasma with the use of the packed chromatographic column 3% OV-101 and the detector of electron capture. The adjustment od plasma is simple. It consists in denaturation of plasma proteins and subsequent simple extraction with benzene.

Optimization of fluorescence detection for the determination of labetalol in plasma by high-performance liquid chromatography.

A sensitive reversed-phase high-performance liquid chromatographic method for the determination of labetalol has been developed. A mobile phase consisting of citrate buffer (pH 6.5), acetonitrile and 2-propanol and an RP-8 column were used.