Publications by authors named "X Q Tuo"
The three-dimensional radiation field is an important database reflecting the radioactivity distribution in a nuclear facility. It is of great significance to accurately and quickly grasp the radiation dose field distribution to implement radiation protection. Presently, majority of radiation field reconstruction algorithms concentrate on two-dimensional reconstruction and can only measure on a regular grid.
View Article and Find Full Text PDFN-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-Q), an oxidative derivative of tire anti-degradant, has been linked to mortality in coho salmon (Oncorhynchus kisutch) and has exhibited potential human toxicity. Hence, exploring how 6PPD-Q interacts with biomacromolecules like enzymes is indispensable to assess its human toxicity and elucidate its mechanism of action. This investigation aims to explore the impact of 6PPD-Q on lactate dehydrogenase (LDH) through various methods.
View Article and Find Full Text PDFBackground: Members of the S100 gene family are frequently dysregulated in various cancers, including ovarian cancer (OC). Despite this, the prognostic implications of individual S100 genes in OC remain poorly understood. This study aimed to explore the prognostic significance of expression in OC and assess its potential as a therapeutic target.
View Article and Find Full Text PDFArticle Synopsis
- * This study focused on developing new quinazoline derivatives to evaluate their antibacterial effectiveness and identify their targets using advanced technologies like activity-based protein profiling (ABPP).
- * The findings revealed that compound 7a showed strong antibacterial effects against a specific pathogen, targeting a key enzyme involved in fatty acid synthesis, while also demonstrating low toxicity to non-target organisms.
Article Synopsis
- Endothelial cell (EC) dysfunction in the aorta contributes to atherosclerosis and complications in vascular grafts, prompting a need for research on its relationship with vascular remodeling.
- This study developed glutamine synthetase (GS) loaded vascular grafts (GSVG) to enhance endothelial metabolism, showing significant improvements in dysfunctional human umbilical vein endothelial cells (HUVECs) in laboratory tests.
- Results indicated that GSVG not only improved EC function but also influenced smooth muscle cell behavior, reduced inflammation, and promoted better vascular graft healing in an animal model.