HDAC11 in ovarian granulosa cells coordinates LH in the maturation of oocytes in Tan sheep.

Oocyte maturation plays an important role in supporting mammalian reproduction. Histone deacetylase 11 (HDAC11), the only member of the class IV histone deacetylase family and the smallest histone deacetylases (HDACs), has been shown to regulate oocyte maturation in mice and pigs. However, the epigenetic effects of HDACs in follicular granulosa cells in response to LH induction remain elusive in sheep.

Design and analysis of teaching early warning system based on multimodal data in an intelligent learning environment.

In online teaching environments, the lack of direct emotional interaction between teachers and students poses challenges for teachers to consciously and effectively manage their emotional expressions. The design and implementation of an early warning system for teaching provide a novel approach to intelligent evaluation and improvement of online education. This study focuses on segmenting different emotional segments and recognizing emotions in instructional videos.

[Constructing disease-specific cohorts of less common tumors based on surgical centers: reflections on the disease-specific cohort of biliary tract cancers].

The incidence of less common tumors is intermediate between rare tumors and high-prevalence tumors,while these less common tumors such as biliary tract cancers generate a significant regional health burden. The overall incidence of less common tumors is relatively low,and thus their clinical epidemiological studies face challenges such as recruitment difficulties,poor representation,and low standardization. Surgical center-based disease-specific cohorts have the advantages of case concentration,complete samples,and well-developed data,which are uniquely valuable in clinical epidemiological studies.

Effect of superficial cervical plexus nerve block with Ropivacaine or a combination of different adjuvants on perioperative analgesia and quality of postoperative recovery in patients undergoing radical thyroid cancer surgery under general anesthesia: a prospective randomized controlled trial.

Objective: To investigate the effect of ultrasound-guided bilateral superficial cervical plexus nerve blocks with Ropivacaine or a combination of different adjuvants on perioperative analgesia and quality of postoperative recovery in patients undergoing radical thyroid cancer surgery under general anesthesia with nerve monitoring without muscarinic maintenance.

Methods: A total of 140 patients undergoing elective radical thyroid cancer surgery were randomly divided into four groups, with 35 cases in each group: general anesthesia alone group (Group C), general anesthesia + Ropivacaine group (Group R), general anesthesia + Ropivacaine combined with dexmedetomidine group (Group R1), and general anesthesia + Ropivacaine combined with dexamethasone group (Group R2). The primary observation index were postoperative resting and active Visual Analogue Score.

Genome-wide identification of glutathione S-transferase (GST) gene family and its regulating characteristics responding to sperm capacitation in Eriocheir sinensis.

Sperm capacitation is regarded to be a process of redox regulation. Within the oxidative regulatory system, glutathione S-transferases (GSTs) are important in the maintenance of the redox balance of reactive oxygen species (ROS). We identify 56 GST genes in the Chinese mitten crab Eriocheir sinensis genome, and categorize them into 13 classes, of which the largest is Mu.