scTRIM44 Positively Regulated Siniperca Chuatsi Rhabdovirus Through RIG-I- and MDA5-Mediated Interferon Signaling.

Tripartite Motif-Containing 44 (TRIM44) is responsible for cancers, neurodegenerative diseases, and viral infections. However, the role of TRIM44 (scTRIM44) during viral infection remains unclear. In the present study, we analyzed the molecular characteristics of scTRIM44 and its role in infectious spleen and kidney necrosis virus (ISKNV), largemouth bass virus (LMBV), and Siniperca chuatsi rhabdovirus (SCRV) infection.

Multi-Component Protein Vaccine Induces a Strong and Long-Term Immune Response Against Monkeypox Virus.

Background/objectives: Since 2022, outbreaks of monkeypox have raised widespread concern and have been declared a public health emergency of international concern by the World Health Organization. There is an urgent need to develop a safe and effective vaccine against the monkeypox virus (MPXV). Recombinant protein vaccines play a significant role in the prevention of infectious diseases due to their high safety and efficacy.

Oral Yeast-Cell Microcapsule-Mediated DNA Vaccines Against Induce Effective Intestinal Immunity and Modulate Gut Microbiota.

is a common opportunistic pathogen that causes gastrointestinal diseases in livestock and poultry. Our preliminary research has demonstrated that administering oral yeast-cell microcapsule (YCM)-mediated DNA vaccines can effectively stimulate mucosal immunity, thereby preventing the occurrence of gastrointestinal diseases. In this study, the α-toxin gene was first cloned and the H126G and C-terminal (C247-370) mutations were created.

Wavelet-Driven Multi-Band Feature Fusion for RGB-T Salient Object Detection.

RGB-T salient object detection (SOD) has received considerable attention in the field of computer vision. Although existing methods have achieved notable detection performance in certain scenarios, challenges remain. Many methods fail to fully utilize high-frequency and low-frequency features during information interaction among different scale features, limiting detection performance.

ppb-Level SO Photoacoustic Sensor for SF Decomposition Analysis Utilizing a High-Power UV Laser with a Power Normalization Method.

A highly sensitive sulfur dioxide (SO) photoacoustic gas sensor was developed for the sulfur hexafluoride (SF) decomposition detection in electric power systems by using a novel 266 nm low-cost high-power solid-state pulse laser and a high -factor differential photoacoustic cell. The ultraviolet (UV) pulse laser is based on a passive -switching technology with a high output power of 28 mW. The photoacoustic signal was normalized to the laser power to solve the fluctuation of the photoacoustic signal due to the power instability of the UV laser.