Non-linear relationship between triglyceride glucose index and new-onset diabetes among individuals with non-alcoholic fatty liver disease: a cohort study.

Background: The relationship between the triglyceride glucose (TyG) values and the development of diabetes in non-alcoholic fatty liver disease (NAFLD) patients is not yet well researched. This study aims to examine how the baseline TyG levels correlate with the incidence of new-onset diabetes in this specific cohort.

Methods: This cohort included 2,506 normoglycemic Japanese adults with NAFLD who underwent routine health check-ups at Murakami Memorial Hospital between 2004 and 2015.

Validation of the Iwate scoring system for the stratification of laparoscopic liver resections: An international multicenter study.

Introduction: The Iwate difficulty scoring system (DSS) is one of the most widely validated DSS for laparoscopic liver resection (LLR). However, these studies only validated the 4 difficulty levels and did not validate the 12-point difficulty index of the system. To address current limitations in the studies validating the Iwate difficulty scoring system (DSS), we performed an international multicenter study to validate the Iwate DSS across both its four difficulty levels and 12-point difficulty index.

Associations of Palmito-leic Acid and Nervonic Acid Hexosylceramides with Type 2 Diabetes Mellitus in a Prospective Nested Case-control Study Among Chinese Population.

Objectives: We aimed to evaluate the associations of hexosylceramides (HexCers) and their ratio with incident type 2 diabetes mellitus (T2DM) and explore underlying mechanisms.

Methods: We conducted a nested case-control study using the Suzhou chronic disease cohort including 234 T2DM cases and 468 controls, 1:2 matched on age (±2 y) and sex. HexCer(d18:1/16:1) and HexCer(d18:1/24:1) were measured by targeted UPLC-MS/MS.

Association between mental health and insomnia in young soldiers: a mediation analysis of mental health literacy.

Background: Military personnel face more stresses and challenges, and they are at greater risk of insomnia compared to the general population. Mental health is one of the primary ways of managing insomnia. However, there are few studies regarding the mediator in the two variables among this population.

Association between serum uric acid to high-density lipoprotein cholesterol ratio and all-cause and cardiovascular disease mortality after stroke: A cross-sectional study from 2005 to 2018.

Background And Aims: The uric acid to high-density lipoprotein cholesterol ratio (UHR) has been shown to be associated with multiple metabolic diseases and inflammation. Stroke is the second leading cause of death and the third leading cause of disability worldwide. This study investigated the relationship between serum UHR and mortality in adults with stroke.