First Determination of the Spin-Parity of Ξ_{c}(3055)^{+,0} Baryons.

The Ξ_{b}^{0(-)}→Ξ_{c}(3055)^{+(0)}(→D^{+(0)}Λ)π^{-} decay chains are observed, and the spin-parity of Ξ_{c}(3055)^{+(0)} baryons is determined for the first time. The measurement is performed using proton-proton collision data at a center-of-mass energy of sqrt[s]=13  TeV, corresponding to an integrated luminosity of 5.4  fb^{-1}, recorded by the LHCb experiment between 2016 and 2018.

The TMBIM1-YBX1 axis orchestrates MDSC recruitment and immunosuppressive microenvironment in pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) is notorious for its profoundly immunosuppressive nature. The complex crosstalk between diverse immune cell types and heterogeneous tumor cell populations shapes this challenging tumor immune microenvironment (TIME). In this study, the role of transmembrane BAX inhibitor motif-containing 1 (TMBIM1) in modulating the TIME and its potential as a therapeutic target in PDAC were investigated.

Study on the mechanical mechanism and control optimization of station subsurface excavation by pile-beam-arch method.

This paper is based on the construction of the underground Pile-Beam-Arch station at Beitaipingzhuang Station of Beijing Metro Line 12. It employs finite element software for three-dimensional numerical modeling, faithfully reproducing the entire station construction process. The results indicate that the excavation of the pilot tunnel and the stage of the secondary lining buckle arch are the main causes of surface deformation.

circEgg inhibits BmCPV infection by regulating the transition between H3K9me3 and H3K9ac.

Our previous study demonstrated that the expression level of circRNA circEgg, which is encoded by histone-lysine N-methyltransferase eggless (BmEgg), is responsive to Bombyx mori cytoplasmic polyhedrosis virus (BmCPV) infection in the silkworm. However, the precise relationship between BmCPV infection and circEgg remains unclear. In this study, we observed that the expression level of circEgg in both the midguts and cultured BmN cells significantly increased after BmCPV infection, while the expression of its host gene, BmEgg, exhibited an opposite trend.