Publications by authors named "X Flores"
Fetal hyperthyroidism is a rare prenatal disease and can be life-threatening. The diagnosis is based on ultrasound in mothers with a history of Basedow-Graves' disease and elevation of thyrotropin receptor antibodies (TRAbs) levels. The treatment consists of antithyroid drugs.
View Article and Find Full Text PDFVentricular fibrillation (VF) in acute myocardial infarction (AMI) is the main cause of deaths occurring in the acute phase of an ischemic event. Although it is known that genetics may play an important role in this pathology, the possible role of long non-coding RNAs (lncRNA) has never been studied. Therefore, the aim of this work is to study the expression of 10 lncRNAs in patients with and without VF in AMI.
View Article and Find Full Text PDFArticle Synopsis
- Intravascular lithotripsy (IVL) is effective for treating calcified coronary lesions in patients with stable coronary disease, as shown in a study involving 426 patients across 26 centers in Spain.
- The study found that IVL was successfully delivered in 99% of cases, achieving procedural success in 66% of patients and similar outcomes for both acute coronary syndrome (ACS) and chronic coronary syndrome (CCS) groups.
- The safety analysis showed a relatively low rate of major adverse cardiovascular events (MACE) at 30 days, with 3% overall (1% for CCS and 5% for ACS), indicating that IVL is both safe and effective in real-life clinical settings.
Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort.
Eur Respir J
November 2023
Article Synopsis
- This global study investigates the long-term outcomes of patients with tuberculosis (TB) and COVID-19, highlighting a lack of prior longitudinal data on this combined condition.
- Data was collected from 788 patients across 31 countries from March 2020 to September 2022, showing a mortality rate of 10.8% during the study period.
- Key factors influencing mortality included older age, HIV infection, and the need for invasive ventilation, with patients suffering from both diseases experiencing significantly lower survival rates compared to those with only one of the diseases.
Article Synopsis
- The study investigates long-term outcomes after ST-segment myocardial infarction (STEMI), focusing on how different adverse events affect patient prognosis over a 10-year period.
- Patients were randomized to receive either an everolimus-eluting stent or a bare-metal stent, and various predictors of composite adverse events (like death or revascularization) were analyzed.
- Results showed that about one-third of patients experienced adverse events, with factors like age and diabetes being significant predictors, but the type of first event (target vessel failure vs. non-target vessel failure) did not significantly impact subsequent outcomes.