Publications by authors named "X Dura-Miralles"

Article Synopsis
  • Hypereosinophilic syndrome can affect the heart and is often linked to poor outcomes, but there's limited data on its impact on Latin American migrants with eosinophilia from parasitic infections.
  • A study was conducted with individuals from Latin America, comparing those with eosinophilia and helminth infections to those without, using echocardiography and microbiological tests for diagnosis.
  • Results showed that participants with eosinophilia had significant echocardiographic changes, like increased heart wall thickness and altered heart function, suggesting early signs of heart dysfunction potentially due to eosinophilia-related effects.
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We assessed the antibiotic use in SARS-CoV-2-infected patients during four different waves of the COVID-19 pandemic, as well as its trends over the period and associated risk factors. We performed a cross-sectional retrospective analysis nested in a prospectively collected cohort of hospitalized adult patients with COVID-19 at a university hospital in Spain. A total of 2415 patients were included in this study, among whom 1120 corresponded to the first wave.

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Objectives: To describe long-COVID symptoms among older adults and to assess the risk factors for two common long-COVID symptoms: fatigue and dyspnea.

Methods: This is a multicenter, prospective cohort study conducted in Israel, Switzerland, Spain, and Italy. Individuals were included at least 30 days after their COVID-19 diagnosis.

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Article Synopsis
  • The study assessed the impact of ceftolozane-tazobactam (C/T) treatment on mortality and mechanical ventilation needs in neutropenic hematologic patients with Pseudomonas aeruginosa bloodstream infections (PA BSI), comparing it to other antibiotic treatments.
  • Out of 132 patients analyzed, a significant majority (91%) had multidrug-resistant PA strains, with pneumonia and endogenous sources being the most common origins for BSI.
  • Results showed that C/T treatment significantly reduced the need for mechanical ventilation and lowered both 7-day and 30-day mortality rates compared to alternative antibiotics in this vulnerable patient population.
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To assess the effect of combination antibiotic empirical therapy on 30-day case-fatality rate in neutropenic cancer patients with Pseudomonas aeruginosa (PA) bacteremic pneumonia. This was a multinational, retrospective cohort study of neutropenic onco-hematological patients with PA bloodstream infection (BSI) (2006−2018). The effect of appropriate empirical combination therapy, appropriate monotherapy and inappropriate empirical antibiotic therapy [IEAT] on 30-day case-fatality was assessed only in patients with PA bacteremic pneumonia.

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