Unveiling the synergistic mechanism of Fe-Cu bimetallic catalysts for degradation of tetracycline antibiotic with ultralow peroxymonosulfate dosage consumption: Key contribution of electron transfer process.

Developing low-oxidant, high efficiency catalysts is critical to meet the green-circular goal in water treatments. Heteroatom-doped graphite-based carbon nitride carrier catalysts are among the most promising candidate materials in water purification catalysis. In this research, a bimetallic catalyst (Fe-Cu@SNC), featuring dual reaction centers, was prepared using a mass-producible co-precipitation method.

Improving auditory alarm sensitivity during simulated aeronautical decision-making: the effect of transcranial direct current stimulation combined with computerized working memory training.

Auditory alarm deafness is a failure to notice a salient auditory signal in a high-load context, which is one of the major causes of flight accidents. Therefore, it is of great practical significance for aviation safety to explore ways to avoid auditory alarm deafness under a high-load scenario. One potential reason for its occurrence could be the fact that cognitive resources are limited.

Over-expression of AeWRKY2 promotes oleanolic acid and hederagenin accumulation in Aralia elata.

Oleanolic acid (OA) and hederagenin from Aralia elata have important medicinal value due to their anti-cancer and anti-inflammatory activities. Transcription factors (TFs) can affect the production of active substances by regulating the expression of genes in metabolic pathways. In this study, a transcription factor AeWRKY2 was cloned and overexpressed in A.

Interfacial engineered biomass-derived G/VMT-PCNCs networks as high-performance proton-conducting humidity sensors.

In this study, a novel proton-conducting film was strategically engineered by interfacial manipulation of green and sustainable biomass resources guanine and phosphorylated cellulose nanocrystals (PCNCs) within vermiculite layers. The interfacial engineering approach involved regulation of molecular interactions at the vermiculite-organic interface, whereby PCNCs were incorporated into the interlayers of guanine/vermiculite composites. This interfacial assembly process guided guanine to form tubular structures or ultrathin nanosheets architectures, enabling the fabrication of guanine/vermiculite-PCNCs (G/VMT-PCNCs) composite films with an active-site-rich and tightly interconnected network via a vacuum-assisted process.

In vivo pharmacodynamic study of the novel polymyxin MRX-8.

In previous studies, polymyxin MRX-8 demonstrated potent in vitro antibacterial activity with a reduced nephrotoxicity risk and an improved PK/PD profile compared with polymyxin B. In this study, the in vivo antibacterial efficacy of intravenously administered MRX-8 was evaluated in murine models of systemic infection (induced by intraperitoneal injection), lung infection (induced by intratracheal route inoculation), and ascending urinary tract infection (induced by intraurethral inoculation) with P. aeruginosa, K.