Haplotypes of Chloroquine Resistance Marker Genes Among Uncomplicated Malaria Cases in Lagos, Nigeria.

Drug resistance resulting from mutations in Plasmodium falciparum, that caused the failure of previously effective malaria drugs, has continued to threaten the global malaria elimination goal. This study describes the profiles of P. falciparum chloroquine resistance transporter (Pfcrt) and P.

Genetic analysis of a pedigree with hereditary coagulation factor XII deficiency.

Analyze the clinical phenotype and gene mutations of a family with hereditary FXII deficiency, and preliminarily explore its phenotypic manifestations. The routine coagulation indicators and related coagulation factors were measured.Thromboelastography and thrombin generation tests simulated coagulation and anticoagulation states in vitro and in vivo.

The combination of and mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and reducing CD8 T cells in mice.

Unlabelled: The gut microbiota is closely associated with inflammatory bowel disease (IBD) and colorectal cancer (CRC). Probiotics such as (CB) or (AKK) have the potential to treat inflammatory bowel disease (IBD) or colorectal cancer (CRC). However, research on the combined therapeutic effects and immunomodulatory mechanisms of CB and AKK in treating IBD or CRC has never been studied.

Novel one-step lignin microsphere preparation for oral tissue regeneration applications.

Lignin is a naturally derived biomacromolecule with excellent biocompatibility and the potential for biomedical application. For the first time, this study isolated nanosized lignin microspheres (LMSs) directly from wheat straw with a polyol-based deep eutectic solvent. The size of these LMSs can be regulated by changing the isolation parameters, ranging from 90 nm to 330 nm.

Exploring the performance of large language models on hepatitis B infection-related questions: A comparative study.

Background: Patients with hepatitis B virus (HBV) infection require chronic and personalized care to improve outcomes. Large language models (LLMs) can potentially provide medical information for patients.

Aim: To examine the performance of three LLMs, ChatGPT-3.