Publications by authors named "X Bertels"

Article Synopsis
  • In April 2024, the European Summit on chronic respiratory diseases (CRDs) was held in the European Parliament, organized by EUFOREA and hosted by MEPs Dorien Rookmaker and Mislav Kolakušić.
  • The Summit aimed to address the challenges faced by European patients with CRDs by fostering collaboration among various European and global health organizations.
  • Representatives from multiple societies and patient associations discussed strategies to improve respiratory care and prevention by sharing their visions and action plans.
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The European Forum for Research and Education in Allergy and Airways diseases (EUFOREA) organized the first European Biologic Training Course (EBTC) in Brussels on 1st March 2024. The aim of this hybrid EBTC including both face-to-face and web-based participation was to address the educational needs of physicians dealing with asthma and Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) on the clinically relevant aspects of diagnosing and treatment with biologics. EUFOREA is an international non-for-profit organization forming an alliance of all stakeholders dedicated to reducing the prevalence and burden of chronic respiratory diseases through the implementation of optimal patient care via educational, research, and advocacy activities.

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Article Synopsis
  • Chronic obstructive pulmonary disease (COPD) can be influenced by genetic factors and may stem from reduced lung growth during childhood, leading to lower lung function throughout life.
  • A polygenic risk score (PRS) was calculated using data from a large genome-wide association study and tested for its correlation with lung function in individuals aged 4-50 from multiple research cohorts.
  • Results indicated that higher PRS scores were associated with significantly lower lung function, measured by key indicators, starting from childhood and continuing into adulthood, regardless of smoking, sex, or asthma diagnosis.
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Research suggests that respiratory and cardiovascular drugs can ameliorate the rate of lung function decline. To investigate the impact of respiratory and cardiovascular pharmacotherapy on lung function trajectories in the general population. Repeated spirometry was performed in the Rotterdam Study, a population-based cohort of adults aged ≥45 years.

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