Publications by authors named "X Alsina-Restoy"
Background: Aerobic capacity has shown to predict physical and mental health-related quality of life in bipolar disorder (BD). However, the correlation between exercise respiratory capacity and mitochondrial function remains understudied. We aimed to assess longitudinally intra-individual differences in these factors during mood episodes and remission in BD.
View Article and Find Full Text PDFBackground: Most patients with haematological malignancies who undergo allogeneic haematopoietic stem cell transplant (HSCT) receive chemotherapy before the transplant to control the disease. Certain chemotherapy drugs can cause lung toxicity. Conversely, in patients with chronic respiratory conditions, the 6-min walking test (6MWT) and the desaturation-distance ratio (DDR) have demonstrated prognostic significance.
View Article and Find Full Text PDFReduced mitochondrial respiratory capacity in patients with acute episodes of bipolar disorder: Could bipolar disorder be a state-dependent mitochondrial disease?
Acta Psychiatr Scand
January 2024
Article Synopsis
- - The study investigates mitochondrial function in patients with bipolar disorder (BD) during mood episodes and after clinical remission, focusing on the differences in mitochondrial respiration between these states and healthy controls.
- - Researchers observed a significant increase in mitochondrial oxygen consumption capacity (specifically electron transport chain activity) in BD patients during remission compared to acute episodes, suggesting improvements in mitochondrial bioenergetics.
- - The study involved 20 BD patients (15 manic and 5 depressive) and 10 healthy controls, highlighting that while the results showed trends of improvement in both mood episodes, the differences were more pronounced in clinical remission.