Publications by authors named "Wynne Aveling"

Article Synopsis
  • - Acute mountain sickness (AMS) affects many during high-altitude ascents, and this study aimed to explore how physiological factors relate to AMS occurrence during a trek to 5300 m.
  • - Out of 332 participants, 73.5% experienced AMS, with 50.3% reporting moderate-to-severe symptoms; those with no prior exposure to altitudes over 5000 m were more at risk.
  • - Key predictors for developing moderate-to-severe AMS included lower peripheral oxygen saturation (SpO) levels during exercise and no previous high-altitude experience, indicating these variables could help anticipate AMS risk in future treks.
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Puerperal sepsis is one of the five leading causes of maternal mortality worldwide, and accounts for 15% of all maternal deaths. The WHO defined puerperal sepsis in 1992 as an infection of the genital tract occurring at any time between the rupture of membranes or labour and the 42nd day post partum; in which, two or more of the following are present: pelvic pain, fever, abnormal vaginal discharge and delay in the reduction of the size of the uterus. At the same time, the WHO introduced the term puerperal infections, which also include non-genital infections in the obstetric population.

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Background: The neuroprotective property of clomethiazole has been demonstrated in several animal models of global and focal brain ischemia. In this study the authors investigated the effect of clomethiazole on cerebral outcome in patients undergoing coronary artery bypass surgery.

Methods: Two hundred forty-five patients scheduled for coronary artery bypass surgery were recruited at two centers and prospectively randomized to clomethiazole edisilate (0.

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