Publications by authors named "Wybe D Kloppenburg"

Article Synopsis
  • The study explores structural brain differences in chronic kidney disease (CKD) patients, particularly focusing on the correlation between these changes and depression.
  • Using MRI scans, researchers found that CKD patients had lower overall gray matter volume and more severe white matter lesions compared to healthy controls, with specific reductions in brain areas related to depression.
  • The findings indicate that while CKD is linked to brain structure changes, the relationship with depression needs further investigation in larger, longitudinal studies to understand the potential risks for CKD patients.
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Background: Protein requirements in stable, adequately dialysed haemodialysis patients are not known and recommendations vary. It is not known whether increasing the dialysis dose above the accepted adequate level has a favourable effect on nutrition. The aim of this study was to determine whether prescribing a high protein diet and increasing the dose of dialysis would have a favourable effect on dietary protein intake and nutritional status in stable, adequately dialysed haemodialysis patients.

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Background: Dietary energy intake (DEI) is reported to be below recommended values in a large proportion of stable chronic haemodialysis patients, while energy requirement appears not to be very different from that in healthy subjects. Nevertheless, body mass has often been reported to be stable over time. We hypothesized that underestimation of habitual DEI by self-reporting of food intake could explain the contradiction of a neutral energy balance despite an apparently insufficient DEI.

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