Publications by authors named "Wuzhou Wu"

CXCL5, a CXC-type chemokine, is an important attractant for granulocytic immune cells by binding to its receptor CXCR2. Recently, CXCL5/CXCR2 has been found to play an oncogenic role in many human cancers. However, the exact role of CXCL5 in osteosarcoma cell migration and invasion has not been revealed.

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Objective: To investigate the expression and clinical significance of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and Kelch-like ECH-associated protein 1 (Keap1) in osteosarcoma tissue.

Methods: The data of 102 osteosarcoma patients who underwent surgical treatment at our hospital from June 2000 to March 2009 were collected. The expression levels of the Nrf2 and Keap1 proteins in osteosarcoma tissue and normal peritumour tissues were detected by immunohistochemistry, and the relationship between the expression level and the clinical and pathological features as well as the prognosis was explored.

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Article Synopsis
  • - This study investigated the link between Helicobacter pylori (HP) infection and periodontal disease (PD) using a case-control approach with patients diagnosed with PD and a control group without PD.
  • - The research involved 212 non-smoking Han Chinese adults and found that being HP-positive significantly increased the risk of developing PD, with an odds ratio of 2.63 before adjustments and 2.82 after accounting for various factors.
  • - The findings suggest that HP infection could be a significant and independent risk factor for periodontal disease in adults.
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