Publications by authors named "Wuzeng Wei"
Osteoarthritis (OA) is a severe disease and has brought a massive burden to people's daily life. This study was performed to explore the hub genes associated with OA and predict potential biomarkers for OA. The cartilage (GSE114007) and synovial (GSE55235 and GSE55457) datasets downloaded from the Gene Expression Omnibus (GEO) database were used to screen the differentially expressed genes in OA compared with normal tissues.
View Article and Find Full Text PDFChanges in regional neural activity and functional connectivity in cervical spondylotic myelopathy (CSM) patients have been reported. However, resting-state cerebral blood flow (CBF) changes and coupling between CBF and functional connectivity in CSM patients are largely unknown. Twenty-seven CSM patients and 24 sex/age-matched healthy participants underwent resting-state functional MRI and arterial spin labeling imaging to compare functional connectivity strength (FCS) and CBF between the two groups.
View Article and Find Full Text PDFBone loss induced by mechanical unloading is a common skeletal disease, but the precise mechanism remains unclear. The current study investigated the role of histone methylation, a key epigenetic marker, and its cross-talk with DNA methylation in bone loss induced by mechanical unloading. The expression of G9a, ubiquitin-like with PHD and ring finger domains 1 (UHRF1), and DNA methylation transferase 1 (DNMT1) were increased in hind limb unloading (HLU) rats.
View Article and Find Full Text PDFBackground: It is estimated that 3%-8% of orthopedic patients, many of whom may undergo lower extremity total joint arthroplasty (TJA), are infected with hepatitis C virus. However, the impact of this virus on total joint arthroplasty is still undefined.
Methods: Eligible studies were searched from electronic databases including PubMed, Web of Science, CNKI and OVID.