Publications by authors named "Wusheng Cai"

Article Synopsis
  • Osteoarthritis (OA) is a common degenerative joint disease linked to mitochondrial dysfunction, which is crucial for energy production and cellular metabolism.
  • Mitochondrial dysfunction in OA is associated with increased oxidative stress, inflammation, abnormal chondrocyte metabolism, and impaired autophagy.
  • The review discusses potential interventions aimed at improving mitochondrial function to slow down or prevent the progression of OA, providing a deeper understanding of the disease's metabolic changes.
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Osteoarthritis (OA) is a common age-related disorder. Chondrocytes in joint tissue play a critical role in normal articular cartilage function and tissue homeostasis. Local inflammatory cytokine-induced chondrocyte senescence contributes to the development and progression of OA.

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