The study aimed to explore the effects of endothelial progenitor cells (EPCs) transplantation on rats suffering from sepsis induced by lipopolysaccharides (LPS).
The experiment involved three groups of rats: a control group, a model group with induced sepsis, and a group receiving EPCs after LPS injection, with various methods used to analyze the results, including imaging, ELISA, and RT-PCR.
Results showed that EPCs successfully localized near blood vessels, and their transplantation significantly reduced inflammation, indicated by lower levels of specific interleukins and improved tissue conditions in lungs, liver, and kidneys.