Publications by authors named "Wunan Huang"
Article Synopsis
- Diabetic nephropathy (DN) is a serious complication of diabetes with no current cure, and this study investigates the protective effects of Huperzine A (Hup A), a natural compound known for its beneficial properties.
- The research was conducted using diabetic rat models, focusing on Hup A's effects on kidney health, lipid metabolism, and gut microbiome balance, with correlations found between various biological data.
- The findings suggest that Hup A improves kidney injury in DN and could serve as a potential treatment for preventing and managing this condition.
Endometrial cancer (EC) is a common malignant tumor that lacks any therapeutic target and, in many cases, recurrence is the leading ca use of morbidity and mortality in women. Widely known EC has a strongly positive correlation with abnormal lipid metabolism. Squalene epoxidase (SQLE), a crucial enzyme in the cholesterol synthesis pathway regulating lipid metabolic processes has been found to be associated with various cancers in recent years.
View Article and Find Full Text PDFBackground/aims: Diabetic retinopathy is the most common eye disease that causes blindness in the working population. Neurodegeneration is the early sign of diabetic retinopathy, but no drug has been approved for delaying or reversing retinal neurodegeneration. Huperzine A, a natural alkaloid isolated from Huperzia serrata, displays neuroprotective and antiapoptotic effects in treating neurodegenerative disorders.
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