Publications by authors named "Wumei Shi"
Article Synopsis
- Wumei Wan (WMW) is a traditional Chinese medicine that shows promise in treating Colitis-associated colorectal cancer (CAC), but its effectiveness across different CAC stages is still being researched.
- The study aims to assess the therapeutic effects of WMW on CAC progression using mouse models, analyzing its chemical components and immune responses through various scientific methods.
- Results reveal that WMW is particularly effective during the early stage of CAC, reducing inflammation, promoting healthier immune activity, and improving tissue condition, while also showing significant gene expression changes related to cancer pathways.
Background: Wumei Wan (WMW) has been used to address digestive disorder for centuries in traditional Chinese medicine. Previous studies have demonstrated its anti-colitis efficacy, but the underlying mechanism of its action remains to be further clarified.
Purpose: To investigate the underlying mechanisms of WMW in the treatment of chronic ulcerative colitis (UC) through network pharmacology and experimental validation.