Drug Delivery Targeting Neuroinflammation to Treat Brain Diseases.

Inflammation within the brain is a hallmark of a wide range of brain diseases. The complex role of inflammatory processes in these conditions suggests that neuroinflammation could be a valuable therapeutic target. While several promising anti-inflammatory agents have been identified, their clinical application in brain diseases is often hampered by the inability to cross the blood-brain barrier (BBB) and reach therapeutically effective concentrations at the pathological sites.

Ca-nano starch-lutein endowed 3D printed surimi with antioxidation and mutual reinforcing transmembrane transport mechanisms via hepg2 and caco-2 cells model.

To better enhance printing effects meanwhile casting functionality, antioxidation and absorption of bioactive component in printed Ca-nano starch (NS)-lutein (L)-surimi were investigated. Results shown that Ca-NS-L promoted surimi printability due to enhanced gel strength and denser structure. Mixing Ca-NS-L endowed printed surimi with antioxidation (DPPH, ABTS, hydroxyl radical, Fe reduction were 42 %, 79 %, 65 %, 0.

A review: Interactions between protein from blue foods and functional components in delivery systems: Function exertion and transmembrane transport by in vitro digestion/cells model.

Functional compounds (FCs) had some functions, which are affected easily by digestion and transmembrane transport leading to low absorption rates, such as lutein, quercetin, xylo-oligosaccharide. Protein from blue foods is a potential bioactive compound, which had higher bioavailability, especially for bioactive peptides (BBPs). The BBPs has great limitations, especially the variability under pepsin digestion.

Ice crystal guided folding of graphene oxides in a confined space: a facile approach to 1D functional graphene structures.

The controlled conformational changes of planar graphene nanosheets are of great importance to the realization of their practical applications. Despite substantial effort in the area, the controlled folding of two-dimensional (2D) graphene sheets into one-dimensional (1D) structures still remains a significant challenge. Here, for the first time, we report an ice crystal guided folding strategy to fabricate 1D folded graphene nanobelts (FGBs), where the formation and growth of ice crystals in a confined space function to guide the folding of 2D graphene oxide (GO) nanosheets into 1D nanobelts ( folded graphene oxide belts, FGOBs), which were subsequently converted to FGBs after annealing.

Cotton-derived three-dimensional carbon fiber aerogel with hollow nanocapsules and ultrahigh adsorption efficiency in dynamic sewage treatment system.

An ultralight 3D carbon fiber aerogel with good flexibility is developed via soaking cotton in water and then calcinating at a high temperature. This cotton-derived carbon material is constituted by amorphous carbon and retains slight oxygen-containing groups. Besides, a lot of hollow carbon nanocapsules are yielded on the inside surface, resulting in abundant micropores and mesopores.

Effect of sulfidation on nitrobenzene removal from groundwater by microscale zero-valent iron: Insights into reactivity, reaction sites and removal pathways.

While it has been recognized that sulfidation can effectively improve the reactivity of microscale zero valent iron (mZVI), there is limited understanding of nitrobenzene (ArNO) removal by sulfidated mZVI. To understand the reduction capacity and pathway of ArNO by sulfidated mZVI, ball-milling sulfidated mZVI (S-mZVI) with different S/Fe molar ratios (0-0.2) was used to conduct this experiment.

Enhanced dechlorination of trichloroethene by sulfidated microscale zero-valent iron under low-frequency AC electromagnetic field.

In this study an electromagnetic heating strategy is proposed for remediation of trichloroethene (TCE) by ball milled, sulfidated microscale zero valent iron (S-mZVI) particles. S-mZVI is ferromagnetic, which generates heat under the application of a low-frequency alternating current electromagnetic field (AC EMF). We found that the temperature reached up to ~120 ℃ during 30-min electromagnetic induction heating of 10 g/L S-mZVI (with S/Fe molar ratio of 0.

One-step hydrothermal synthesis of hierarchical nanosheet-assembled BiOCO microflowers with a {001} dominant facet and their superior photocatalytic performance.

Using citric acid (CA) and 1,5-naphthalenedisulfonic acid (NDSA) as the structure-directing agent, a hierarchical flower-like BiOCO product is successfully prepared via a simple one-step hydrothermal synthesis, which is spirally assembled by the {001} facet-dominated nanosheets. It is testified that the additive CA plays an important inducing role in forming the chemical composition of BiOCO, the nanosized sheet-type subunits, and the exposure of the {001} facet, while the NDSA greatly improves the dispersity and porous structure of the BiOCO microflower. Due to the nano-size effect and distortion of surface Bi-O bonds, the BiOCO microflower could be excited by the visible light to exhibit a superior photocatalytic performance in the degradation of tetracycline (TC).

Metal Foam-Based Fenton-Like Process by Aeration.

A novel metal foam-based Fenton-like process for wastewater treatment is illustrated in this study. In the system, HO was generated in situ by taking advantage of O in air, as metal could activate dissolved O to produce O and then generate HO. Furthermore, metal foam can enhance the Fe/Fe cycling, which eventually improved the efficiency of the Fenton process.

Rapid and highly selective removal of lead from water using graphene oxide-hydrated manganese oxide nanocomposites.

To overcome the limits of graphene oxide (GO) as a novel sorbent for heavy metal removal (e.g., low sorption selectivity and difficulty in solid-liquid separation), a nanocomposite (HMO@GO) with excellent settling ability (<2min) was fabricated through in situ growing nanosized hydrated manganese oxide (HMO) (10.

Multifunctional nitrogen-doped graphene nanoribbon aerogels for superior lithium storage and cell culture.

Nitrogen-doped graphene nanoribbon aerogels (N-GNRAs) are fabricated through the self-assembly of graphene oxide nanoribbons (GONRs) combined with a thermal annealing process. Amino-groups are grafted to the surface of graphene nanoribbons (GNRs) by an epoxy ring-opening reaction. High nitrogen doping level (7.

Thermal Modelling Analysis of Spiral Wound Supercapacitor under Constant-Current Cycling.

A three-dimensional modelling approach is used to study the effects of operating and ambient conditions on the thermal behaviour of the spiral wound supercapacitor. The transient temperature distribution during cycling is obtained by using the finite element method with an implicit predictor-multicorrector algorithm. At the constant current of 2A, the results show that the maximum temperature appears in core area.

Polymer/graphene hybrid aerogel with high compressibility, conductivity, and "sticky" superhydrophobicity.

The idea of extending functions of graphene aerogels and achieving specific applications has aroused wide attention recently. A solution to this challenge is the formation of a hybrid structure where the graphene aerogels are decorated with other functional nanostructures. An infiltration-evaporation-curing strategy has been proposed by the formation of hybrid structure containing poly(dimethylsiloxane) (PDMS) and compressible graphene aerogel (CGA), where the cellular walls of the CGA are coated uniformly with an integrated polymer layer.

Highly atom-economic synthesis of graphene/Mn₃O₄ hybrid composites for electrochemical supercapacitors.

A highly atom-economic procedure for the preparation of reduced graphene oxide/Mn3O4 (rGO/Mn3O4) composites is reported. Pristine graphene oxide/manganese sulfate (GO/MnSO4) suspension produced by modified Hummers method is utilized with high efficiency, which has been in situ converted into GO/Mn3O4 hybrid composite by air oxidation, then into rGO/Mn3O4 composite by means of dielectric barrier discharge (DBD) plasma-assisted deoxygenation. The Mn3O4 content of the rGO/Mn3O4 composites can be readily tailored.

Ultralight and highly compressible graphene aerogels.

Chemically converted graphene aerogels with ultralight density and high compressibility are prepared by diamine-mediated functionalization and assembly, followed by microwave irradiation. The resulting graphene aerogels with density as low as 3 mg cm(-3) show excellent resilience and can completely recover after more than 90% compression. The ultralight graphene aerogels possessing high elasticity are promising as compliant and energy-absorbing materials.