Research on Visual-Inertial Measurement Unit Fusion Simultaneous Localization and Mapping Algorithm for Complex Terrain in Open-Pit Mines.

As mining technology advances, intelligent robots in open-pit mining require precise localization and digital maps. Nonetheless, significant pitch variations, uneven highways, and rocky surfaces with minimal texture present substantial challenges to the precision of feature extraction and positioning in traditional visual SLAM systems, owing to the intricate terrain features of open-pit mines. This study proposes an improved SLAM technique that integrates visual and Inertial Measurement Unit (IMU) data to address these challenges.

Bolus delivery of palonosetron through skin by tip-loaded dissolving microneedles with short-duration iontophoresis: A potential strategy to rapidly relieve emesis associated with chemotherapy.

The objective of this study was to investigate the feasibility of the bolus administration of PLS via skin by using dissolving microneedles of palonosetron hydrochloride (PLS-DMNs). Tip-loaded PLS-DMNs were fabricated by a casting method using sodium hyaluronate (HA) as DMNs-forming polymer. PLS-DMNs were shown to have a content of 118.