Publications by authors named "WuYang Yang"
Background And Objectives: The optimal management strategy for pediatric patients with symptomatic moyamoya disease (MMD) is not well established. This systematic review and meta-analysis compares surgical vs conservative management and direct/combined bypass (DB/CB) vs indirect bypass (IB) for pediatric patients with symptomatic MMD.
Methods: MEDLINE and PubMed were searched from inception to March 17, 2024.
Background: The benefit of distal embolite penetration for middle meningeal artery (MMA) embolization in chronic subdural hematomas (cSDH) remains controversial.
Objective: To compare the use of diluted Onyx with undiluted Onyx in the management of cSDH.
Methods: This is a retrospective study of patients with cSDH who underwent MMA embolization using Onyx 18 at our institution.
Article Synopsis
- The study investigates the outcomes and risks associated with ruptured high-grade brain arteriovenous malformations (bAVMs), aiming to clarify decision-making in treating this rare condition.
- It analyzes data from 84 patients treated from 1990 to 2020, focusing on annual hemorrhagic risks and treatment effectiveness, indicating different outcomes for surgery, radiosurgery, and embolization.
- Results show that while surgery reduces the risk of future hemorrhages significantly, embolization increases the risk, with patient quality of life and mortality rates remaining similar across treatment methods.
Background: Transradial approach (TRA) has been increasingly utilized in various neuroendovascular interventions as a safe alternative to the transfemoral approach (TFA). As middle meningeal artery (MMA) embolization emerges as an effective therapy for treating chronic subdural hematomas (cSDH), some studies have explored using TRA. In this study, we compared procedural times and post-operative outcomes between those with TRA and TFA.
View Article and Find Full Text PDFBackground: Middle meningeal artery (MMA) embolization for the treatment of chronic subdural hematomas (cSDHs) is becoming increasingly prevalent. It is essential to optimize the safety and cost effectiveness of the postprocedural management. In this study, we examined our cases over time to determine the most appropriate postprocedural destination.
View Article and Find Full Text PDFBackground: Intraventricular hemorrhage (IVH) refers to bleeding within the brain's ventricular system, and hydrocephalus is a life-threatening complication of IVH characterized by increased cerebrospinal fluid accumulation in the ventricles resulting in elevated intracranial pressure. IVH poses significant challenges for healthcare providers due to the complexity of the underlying pathophysiology and lack of standardized treatment guidelines. Herein, we performed a systematic review of the treatment strategies for hydrocephalus secondary to IVH.
View Article and Find Full Text PDFBackground: Hemorrhagic conversion (HC) is a known complication after acute ischemic stroke (AIS) in patients undergoing mechanical thrombectomy (MT). Although symptomatic HC has been shown to lead to poor neurologic outcomes, the effect of asymptomatic HC (aHC) is unclear. This study aims to identify predictors of aHC and to determine the short-term outcomes.
View Article and Find Full Text PDFObjective: The longitudinal management of unruptured brain arteriovenous malformation (bAVM) is crucial. To date, no study in the United States has evaluated the impact of socioeconomic status (SES) on bAVM outcome. Herein, the authors aimed to clarify the impact of SES, as indicated by the area deprivation index (ADI), on bAVM outcome.
View Article and Find Full Text PDFObjective: A direct-aspiration first-pass technique (ADAPT) in mechanical thrombectomy has been described in recent studies as an efficacious strategy compared with using a stent retriever (SR). We sought to evaluate for cost differences of ADAPT technique versus SR as an initial approach.
Methods: We conducted a retrospective analysis of consecutive patients with mechanical thrombectomy at our institution between 2022 and 2023.
Background Context: The optimal decompression time for patients presenting with acute traumatic central cord syndrome (ATCCS) has been debated, and a high level of evidence is lacking.
Purpose: To compare early (<24 hours) versus late (≥24 hours) surgical decompression for ATCCS.
Study Design: Systematic review and meta-analysis.
Article Synopsis
- This study examines the impact of two hemodialysis methods—continuous venovenous hemodialysis (CVVHD) and intermittent hemodialysis (iHD)—on the rates of subdural hematoma (SDH) re-expansion in patients with end-stage renal disease (ESRD).
- Researchers found that patients undergoing CVVHD had lower rates of SDH expansion affecting neurological function compared to those on iHD, highlighting a significant difference in outcomes between the two methods.
- The conclusion suggests that CVVHD may provide better stability for SDH in ESRD patients, indicating a potential preference for this dialysis approach in their treatment.
Objective: Decision-making for the management of ruptured deep-seated brain arteriovenous malformations (bAVMs) is controversial. This study aimed to shed light on the treatment outcomes of patients with ruptured deep-seated bAVMs.
Methods: Data on bAVM patients were retrieved from the authors' institutional database, spanning 1990-2021.
Background And Objectives: Natural history of hemorrhage in brain arteriovenous malformations (bAVM) is reported at 2%-4% per year. Published studies using survival analysis fail to account for recurrent hemorrhagic events. In this study, we present a large, single institution series to elucidate the natural history of bAVM using multivariable Poisson regression.
View Article and Find Full Text PDFBackground And Objectives: Awake vs asleep craniotomy for patients with eloquent glioma is debatable. This systematic review and meta-analysis sought to compare awake vs asleep craniotomy for the resection of gliomas in the eloquent regions.
Methods: MEDLINE and PubMed were searched from inception to December 13, 2022.
Article Synopsis
- Trigeminal neuralgia (TN) is a type of facial pain that can sometimes be linked to a brain problem called a brain arteriovenous malformation (bAVM), which is very rare.* -
- In a study involving 57 patients, 8 of them had TN because of bAVMs, and different treatments were used, like medicine and surgery.* -
- Most patients who had radiosurgery for their bAVMs saw their facial pain go away completely after a few months, and it worked better for those with TN than in patients without it.*
Background: Tarlov cysts are perineural collections of cerebrospinal fluid most often affecting sacral nerve roots, which may cause back pain, extremity paresthesias and weakness, bladder/bowel dysfunction, and/or sexual dysfunction. The most effective treatment of symptomatic Tarlov cysts, with options including non-surgical management, cyst aspiration and injection of fibrin glue, cyst fenestration, and nerve root imbrication, is debated.
Methods: Retrospective chart review was conducted for 220 patients with Tarlov cysts seen at our institution between 2006 and 2021.
Objective: The treatment experience and the technical skill with percutaneous balloon compression (PBC) for treatment of primary trigeminal neuralgia (TN) were summarised in a single institution.
Methods: This is a retrospective review including consecutive patients with typical symptoms of uni-lateral primary TN who underwent PBC from June 2020 to September 2021 in our institution. We excluded secondary aetiologies of TN.
Background And Objectives: Flow diversion of intracranial aneurysms results in high occlusion rates. However, 10% to 20% remain persistently filling at 1 year. Often, these are retreated, but benefits of retreatment are not well established.
View Article and Find Full Text PDFDifferent types of percutaneous endovascular interventions for acute ischemic stroke.
Cochrane Database Syst Rev
May 2023
Article Synopsis
- Acute ischemic stroke (AIS) is when blood flow to the brain suddenly stops, causing problems with how the brain works.
- This study looks at different procedures doctors can use to treat AIS and compares how safe and effective they are.
- Researchers reviewed many scientific trials to find the best treatments for adults with AIS caused by blocked blood vessels.
Background: Randomized controlled trials comparing endovascular thrombectomy (EVT) versus EVT preceded by intravenous thrombolysis (EVT + IVT) for acute ischemic stroke due to large artery occlusion remain controversial. This systematic review and meta-analysis seek to compare these 2 modalities.
Methods: Online Protocol is available at PROSPERO (york.
Background And Objective: Although randomized controlled trials have compared surgery versus endovascular treatment for intracranial aneurysms, the literature is sparse in terms of subgroup analysis for anterior communicating artery (ACoA) aneurysm management. This systematic review and meta-analysis sought to compare surgical versus endovascular treatment for ACoA aneurysms.
Methods: Medline, PubMed, and Embase were searched from inception to December 12, 2022.
Background: Treatment decision-making for brain arteriovenous malformations (bAVMs) with microsurgery or stereotactic radiosurgery (SRS) is controversial.
Objective: To conduct a systematic review and meta-analysis to compare microsurgery vs SRS for bAVMs.
Method: Medline and PubMed were searched from inception to June 21, 2022.
Background: The results from studies that compare middle meningeal artery (MMA) embolization vs conventional management for patients with chronic subdural hematoma are varied.
Objective: To conduct a systematic review and meta-analysis on studies that compared MMA embolization vs conventional management.
Methods: Medline, PubMed, and Embase databases were searched.