Publications by authors named "Wu-Qiao Bao"
Identification and validation of ion channels-related mRNA prognostic signature for glioblastomas.
Medicine (Baltimore)
November 2024
Article Synopsis
- Glioblastomas (GBM) are aggressive brain tumors with a poor outlook, prompting research into new biomarkers for potential treatments through analyzing mRNA-seq and clinical data from major databases.
- A risk model was developed based on three ion channel-related genes, which indicated that higher risk scores correlate with increased immune cell infiltration and drug sensitivity for GBM.
- Functional analyses and a regulatory network were constructed to explore gene interactions, revealing that two of the genes (GJB2 and KCNN4) were upregulated in the high-risk group, while another (KCNH6) was downregulated.
The study aimed to develop simulation models including intracranial aneurysmal and parent vessel geometries, as well as vascular branches, through 3D printing technology. The simulation models focused on the benefits of aneurysmal treatments and clinical education. This prospective study included 13 consecutive patients who suffered from intracranial aneurysms confirmed by digital subtraction angiography (DSA) in the Neurosurgery Department of Shaoxing People's Hospital.
View Article and Find Full Text PDFMorphological Effect on Wall Shear Stress in Intracranial Aneurysms.
J Neurol Surg A Cent Eur Neurosurg
March 2018
Background And Study Aims: Both high and low wall shear stress (WSS) play important roles in the development and rupture of intracranial aneurysms (IAs). This study aimed to determine the morphological factors that affect WSS in the IA and the parent artery.
Material And Methods: We studied a total of 66 IAs with three-dimensional imaging.