DYNC1H1 variants associated with infant-onset epilepsy without neurodevelopmental disorders.

Objectives: The DYNC1H1 variants are associated with abnormal brain morphology and neuromuscular disorders that are accompanied by epilepsy. This study aimed to explore the relationship between DYNC1H1 variants and epilepsy.

Materials And Methods: Trios-based whole-exome sequencing was performed on patients with epilepsy.

Behaviors of photovoltaic cells illuminated by a laser of different operation modes.

The ultimate capability of light-electricity conversion of a laser with different operation modes in a typical photovoltaic (PV) cell was investigated for the technologic concept of laser power transmission (LPT). The quasi-linear correlation between the maximum allowable laser power density and the pulsed laser power percentage (PPP) of the combined dual lasers was found experimentally on a tri-junction GaAs PV cell. At the same time, the patterns of thermomechanical damage in the PV cells were characterized.

Invariant in variants.

The coronavirus Covid-19 mutates quickly in the pandemic, leaves people struggling to verify and improve the effectiveness of the vaccine based on biochemistry. Is there any physical invariant in the variants of such kind of pathogen that could be taken advantage to ease the tensions? To this point, extensive numerical experiments based on continuity mechanics have been accomplished to discover the consistent vibration modes and the range of natural frequency of coronavirus Covid-19. Such invariant could help us in developing some flexible technique to deactivate the coronavirus, like as resonantly breaking the viral spike by ultrasound wave.

Microstructure Dependence of Effective Thermal Conductivity of EB-PVD TBCs.

Microstructure dependence of effective thermal conductivity of the coating was investigated to optimize the thermal insulation of columnar structure electron beam physical vapor deposition (EB-PVD coating), considering constraints by mechanical stress. First, a three-dimensional finite element model of multiple columnar structure was established to involve thermal contact resistance across the interfaces between the adjacent columnar structures. Then, the mathematical formula of each structural parameter was derived to demonstrate the numerical outcome and predict the effective thermal conductivity.