Publications by authors named "Wu Chang-Zhe"

Our previous study revealed that early application of electrical field stimulation (EFS) with the anode at the lesion and the cathode distal to the lesion reduced injury potential, inhibited secondary injury and was neuroprotective in the dorsal corticospinal tract after spinal cord injury (SCI). The objective of this study was to further evaluate the effect of EFS on protection of anterior horn motoneurons and their target musculature after SCI and its mechanism. Rats were randomized into three equal groups.

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Effective repair immediately after spinal cord injury can improve the prognosis of the patient. Injection of membrane resealing nanomaterial is one of the most promising technique to repair the membrane. In order to improve the retention rate of membrane repair material at injury site, membrane resealing nanomaterial can be combined with magnetic nanoparticle and magnetic targeting system.

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Article Synopsis
  • - A model for action potentials in nerve fibers exists, but current literature lacks a comprehensive model for understanding injury potentials resulting from nerve damage.
  • - This paper proposes a model that describes the electrical behavior of myelinated nerves after an injury, allowing the calculation of time-varying currents and potentials at different nodes of the nerve.
  • - The model demonstrates that the injury potential decreases over time in an exponential manner, with its initial amplitude being influenced by the severity of the injury and the diameter of the nerve fibers.
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Transcranial magnetic stimulation (TMS) is a non-invasive diagnostic and therapeutic technigue. This paper expounds the design and manufacture of the TMS system, which meets all the requirements of the TMS study and clinical diagnosis and treatments.

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