One hundred and twenty-nine specimens of human cutaneous nerve obtained from patients suffering from a variety of neuromuscular disorders have been surveyed in detail by electron microscopy. The most striking finding was the presence of lamellated Schwann cell inclusions and of cells containing vacuoles, both of which appear to be derived from myelin and to show some correlation with sensory loss.
View Article and Find Full Text PDFJ Obstet Gynaecol Br Commonw
December 1964
Acta Neurochir (Wien)
December 1996
A patient with progressive multifocal leucoencephalopathy was found to have primary hypersplenism, a benign disorder of the reticuloendothelial system. He failed to respond to conventional doses of corticosteroids. The clinical and pathological manifestations of his illness are described, and the development of the histopathological changes in the nervous system is discussed.
View Article and Find Full Text PDFJ Neuropathol Exp Neurol
January 1962
Human peripheral nerves obtained by biopsy from patients suffering from neuromuscular disorders have been studied by x-ray diffraction and electron microscopy. Few abnormal diffraction patterns have yet been recorded and their significance is not yet established. Electron micrographs have revealed wide variations in the numbers of myelinated fibres included in the nerve trunks and have facilitated a detailed study of the Schwann cell-axon relationships in the large numbers of unmyelinated fibres always present.
View Article and Find Full Text PDFJ Neurol Neurosurg Psychiatry
November 1960
J Neurol Neurosurg Psychiatry
November 1957
Ned Tijdschr Geneeskd
August 1957