Outcome following radiotherapy for head and neck basal cell carcinoma with 'aggressive' features.

Objectives: The literature demonstrates that 'aggressive' head-and-neck basal cell carcinomas (HN-BCC) have a higher than expected relapse rate with unfavorable outcomes. We report outcomes following definitive (dRT) or post-operative radiotherapy (PORT) for these tumors.

Methods: We reviewed all HN-BCC patients with 'aggressive' features (primary lesions diameter >10mm, >2 recurrences, or extra-cutaneous extension), treated with megavoltage dRT or PORT between 1998 and 2013.

Limited-stage mantle cell lymphoma: treatment outcomes at the Princess Margaret Hospital.

Mantle-cell lymphoma (MCL) is a rare cancer, with the majority of patients (pts) presenting in stage III-IV and the outcomes are poor. To determine the curability of localized MCL, we examine stage I-II pts at our institution between 1990-2007. 26 pts with stage I (38%) and stage II (62%) were referred.

Identifying motivations and barriers to patient participation in clinical trials.

Background: This study assessed cancer patients' knowledge and attitudes towards clinical trials (CTs).

Methods: A survey was administered to 100/141 cancer outpatients.

Results: 82% respondents had heard of CTs, but many could only provide limited definitions and perceived them as high risk.