Publications by authors named "Woodrow D Benson"
Article Synopsis
- Hypoplastic left heart syndrome (HLHS) is a serious heart defect involving underdevelopment of the left ventricle and associated structures, leading to significant health risks despite advances in treatment.
- Genetic factors play a key role in HLHS, with links to cytogenetic abnormalities, familial patterns, and identified genomic regions, suggesting a hereditary basis.
- Identifying specific genetic causes is challenging; HLHS appears to result from complex inheritance rather than a single variant, prompting researchers to adopt more sophisticated models in their studies.
Presence of mechanical dyssynchrony in Duchenne muscular dystrophy.
Kan N Hor Janaka P Wansapura Hussein R Al-Khalidi William M Gottliebson Michael D Taylor Woodrow D Benson
J Cardiovasc Magn Reson
February 2011
Background: Cardiac dysfunction in boys with Duchenne muscular dystrophy (DMD) is a leading cause of death. Cardiac resynchronization therapy (CRT) has been shown to dramatically decrease mortality in eligible adult population with congestive heart failure. We hypothesized that mechanical dyssynchrony is present in DMD patients and that cardiovascular magnetic resonance (CMR) may predict CRT efficacy.
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