Background: Metabolic syndrome (MetS) is characterized by the coexistence of disorders such as diabetes, hypertension, hyperlipidemia, and obesity and is affected by genetic factors. Previous genome-wide association studies (GWAS) suggested that APOA5 gene variants were significantly associated with MetS and its components. Dietary factors such as red and processed meat consumption can cause chronic diseases, including hypertension, diabetes, and vascular depression.
View Article and Find Full Text PDFCyclin-dependent kinase 5 regulatory subunit-associated protein 1-like 1 () is one of the strongest diabetes loci identified to date; evidence suggests that it plays an important role in insulin secretion. Dietary factors that affect insulin demand might enhance the risk of diabetes associated with variants. Our aim was to examine the interactions between dietary protein and fat intake and genetic variants in relation to the risk of diabetes in Korean adults.
View Article and Find Full Text PDFThe aim of the present study was to determine whether the application of isometric horizontal abduction (IHA) differentially affected two weight-bearing push-up plus exercises by examining activation of the scapulothoracic muscles in subjects with scapular winging. Fifteen male subjects performed standard push-up plus (SPP) and wall push-up plus (WPP), with and without IHA. Two-way analyses of variance using two within-subject factors were used to determine the statistical significance of observed differences in upper trapezius (UT), pectoralis major (PM), and serratus anterior (SA) muscle activities and UT/SA and PM/SA muscle activity ratios.
View Article and Find Full Text PDFObjectives: The objective of this study was to introduce levator scapulae (LS) measurement using a caliper and the levator scapulae index (LSI) and to investigate intra- and interrater reliability of the LSI in subjects with and without scapular downward rotation syndrome (SDRS).
Design: Two raters measured LS length twice in 38 subjects (19 with SDRS and 19 without SDRS).
Main Outcome Measures: For reliability testing, intraclass correlation coefficients (ICCs), standard error of measurement (SEM), and minimal detectable change (MDC) were calculated.
Scapular dyskinesis, characterized by scapular downward rotation syndrome (SDRS) affects scapula-humeral rhythm and results in shoulder dysfunction. Previous study has led to the recommendation of standard shrug exercise to contend with SDRS and strengthen the upper trapezius (UT) muscle. However, few researchers have examined which shrug exercise is most effective.
View Article and Find Full Text PDFObjectives: To compare scapular posterior tilting exercise alone and scapular posterior tilting exercise after pectoralis minor (PM) stretching on the PM index (PMI), scapular anterior tilting index, scapular upward rotation angle, and scapular upward rotators' activity in subjects with a short PM.
Participants: Fifteen subjects with a short PM participated in this study.
Main Outcome Measures: The PMI, scapular anterior tilting index, and scapular upward rotation angle were measured after scapular posterior tilting exercise alone and scapular posterior tilting exercise after PM stretches.
The aim of this research was to investigate which shoulder abduction angle (30°, 90°, 150°) during shrug exercise is superior for (1) activating the scapular upward rotators and (2) improving scapular and clavicular position in subjects with scapular downward rotation impairment. Twenty subjects performed shrug exercises at three different shoulder abduction angles (30°, 90°, 150°) which were obtained and maintained actively. Surface EMG data were collected from the levator scapulae (LS), upper trapezius (UT), lower trapezius (LT), and serratus anterior (SA) during shrug exercises.
View Article and Find Full Text PDFBackground And Purpose: The aim of this study was to compare the trunk muscle activities and the local/global activity ratios of the abdominal, back and trunk muscles during stabilization exercises such as one arm raise (AR), one leg raise (LR), and opposing arm/leg raise (ALR) in patients with chronic low back pain (LBP).
Method: Ten individuals with chronic LBP (five men and five women) participated in this study. The external oblique abdominis, internal oblique abdominis, multifidus, thoracic part of the lumbar iliocostalis and the local/global activity ratio were assessed, while quadruped stabilization exercises were performed (AR, LR, and ALR); each exercise was carried out three times.
Background: There are various methods for rehabilitating round-shoulder posture (RSP), including strengthening exercises, stretching, and using a shoulder brace or taping to correct the altered posture. However, no study has determined which intervention is the most effective of the three methods to decrease RSP (intervention #1: scapular posterior tilting exercise alone [hereafter, SPT], intervention #2: the scapular posterior tilting exercise after PM stretching [PM stretch+SPT], and intervention #3: the scapular posterior tilting exercise with use of a shoulder brace [SPT+brace]).
Objectives: The purpose of this study was to compare the SPT, PM stretch+SPT, and SPT+brace on RSP, PM index (PMI), and lower trapezius (LT) and serratus anterior (SA) activity in subjects with RSP.
The purpose of this study was to investigate the effects of bridging with isometric hip abduction (IHA) using the Thera-Band on gluteus maximus (GM), hamstring (HAM), and erector spinae (ES) muscle activity; GM/HAM and GM/ES ratios; and the anterior pelvic tilt angle in healthy subjects. Twenty-one subjects participated in this study. Surface EMG was used to collect EMG data of GM, HAM, and ES muscle activities, and Image J software was used to measure anterior pelvic tilt angle.
View Article and Find Full Text PDFThe purpose of this study was to establish the effects of different hip rotations during isometric side-lying hip abduction (SHA) in subjects with gluteus medius (Gmed) weakness by investigating the electromyographic (EMG) amplitude of the Gmed, tensor fasciae latae (TFL) activity, and gluteus maximus (Gmax), and the activity ratio of the Gmed/TFL, Gmax/TFL, and Gmed/Gmax. Nineteen subjects with Gmed weakness were recruited for this study. Subjects performed three isometric hip abductions: frontal SHA with neutral hips (SHA-N), frontal SHA with hip medial rotation (SHA-MR), and frontal SHA with hip lateral rotation (SHA-LR).
View Article and Find Full Text PDFPreviously we have formulated a new cationic emulsion, composed of 3beta [N-(N',N'-dimethylaminoethane) carbamoyl] cholesterol and dioleoylphosphatidyl ethanolamine, castor oil and Tween 80, and it efficiently delivered plasmid DNA into various cancer cells with low toxicity. Chitosan is a natural cationic polysaccharide and is able to form polyelectrolyte complexes with DNA, in which the DNA is condensed and protected against nuclease degradation. Based on these facts, chitosan was used as a condensing agent to enhance the transfection efficiency of cationic emulsion-mediated gene delivery vehicle.
View Article and Find Full Text PDFCationic liposome has been studied as one of the most promising non-viral gene delivery systems. However, it has major drawbacks such as the formation of large aggregates at higher concentrations and the instability in the serum due to cationic lipid. As an alternative gene delivery system, cationic emulsion was formulated and transfection efficiency was evaluated in vitro and in vivo, in comparison with cationic liposome.
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