Mechanical and biological complications of angled versus straight screw channel implant-supported prostheses: A systematic review and meta-analysis.

Statement Of Problem: Scientific evidence to determine the clinical performance of angled screw channel (ASC) versus straight screw channel (SC) implant-supported prostheses is lacking.

Purpose: This systematic review and meta-analysis investigated the mechanical and biological complications of ASC compared with those of SC implant-supported prostheses.

Material And Methods: A systematic search was conducted by following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guideline in the PubMed, Embase, and Web of Science databases and was supplemented with a manual search for clinical studies reporting the mechanical and biological complications of ASC compared with those of SC implant-supported prostheses.

Machine learning derived serum creatinine trajectories in acute kidney injury in critically ill patients with sepsis.

Background: Current classification for acute kidney injury (AKI) in critically ill patients with sepsis relies only on its severity-measured by maximum creatinine which overlooks inherent complexities and longitudinal evaluation of this heterogenous syndrome. The role of classification of AKI based on early creatinine trajectories is unclear.

Methods: This retrospective study identified patients with Sepsis-3 who developed AKI within 48-h of intensive care unit admission using Medical Information Mart for Intensive Care-IV database.

A novel method leveraging time series data to improve subphenotyping and application in critically ill patients with COVID-19.

Computational subphenotyping, a data-driven approach to understanding disease subtypes, is a prominent topic in medical research. Numerous ongoing studies are dedicated to developing advanced computational subphenotyping methods for cross-sectional data. However, the potential of time-series data has been underexplored until now.

Joint Modeling of Social Determinants and Clinical Factors to Define Subphenotypes in Out-of-Hospital Cardiac Arrest Survival: Cluster Analysis.

Background: Machine learning clustering offers an unbiased approach to better understand the interactions of complex social and clinical variables via integrative subphenotypes, an approach not studied in out-of-hospital cardiac arrest (OHCA).

Objective: We conducted a cluster analysis for a cohort of OHCA survivors to examine the association of clinical and social factors for mortality at 1 year.

Methods: We used a retrospective observational OHCA cohort identified from Medicare claims data, including area-level social determinants of health (SDOH) features and hospital-level data sets.

Peripheral Transcriptomics in Acute and Long-Term Kidney Dysfunction in SARS-CoV2 Infection.

Background: Acute kidney injury (AKI) is common in hospitalized patients with SARS-CoV2 infection despite vaccination and leads to long-term kidney dysfunction. However, peripheral blood molecular signatures in AKI from COVID-19 and their association with long-term kidney dysfunction are yet unexplored.

Methods: In patients hospitalized with SARS-CoV2, we performed bulk RNA sequencing using peripheral blood mononuclear cells(PBMCs).

Discrepancy between predicted and measured exercise intensity for eliciting the maximal rate of lipid oxidation.

Background And Aims: Ectopic lipid storage is implicated in type 2 diabetes pathogenesis; hence, exercise to deplete stores (i.e., at the intensity that allows for maximal rate of lipid oxidation; MLO) might be optimal for restoring metabolic health.

The Influence of Urban Gardening Activities on Participants' Perceived Restorativeness, Resilience, Sense of Community and Stress.

This study aimed to investigate the influence of urban garden activities on participants' perceived restorativeness, resilience, sense of community, and stress reduction. A total of ninety individuals who agreed to participate in the experiment were divided into experimental and control groups. To collect data, 16 sessions of urban garden activities were conducted every two weeks from May to November 2022.

Impact of Vaccination on Major Adverse Cardiovascular Events in Patients With COVID-19 Infection.

Taken from the largest U.S. cohort of patients with SARS-CoV2, our results demonstrate the association of even partial vaccination with lower risk of MACE after SARS-CoV-2 infection.

Federated Learning in Health care Using Structured Medical Data.

The success of machine learning-based studies is largely subjected to accessing a large amount of data. However, accessing such data is typically not feasible within a single health system/hospital. Although multicenter studies are the most effective way to access a vast amount of data, sharing data outside the institutes involves legal, business, and technical challenges.

High physical activity alleviates the adverse effect of higher sedentary time on the incidence of chronic kidney disease.

Background: Low physical activity (PA) increases the prevalence of chronic kidney disease (CKD). This study aimed to investigate the effects of PA and sedentary time (ST) on the changes in renal function and the development of CKD in the middle-aged Korean population.

Methods: From the Korean Genome and Epidemiology Study Database, 7988 participants in their 40s and 60s were identified and stratified by (1) PA: high-PA (>24 MET-h/day), moderate-PA (9-24 MET-h/day) and low-PA (<9 MET-h/day); and (2) ST: high-ST (>6 h/day), moderate-ST (3-6 h/day) and low-ST (<3 h/day).

Digital workflow for creating a coolant channel for direct irrigation through an implant surgical guide.

Heat elicited during the osteotomy for implant placement may have a significant impact on the vitality of surrounding bone and on the healing capacity for osseointegration. This article describes a digital workflow for creating a coolant channel for the direct irrigation of the osteotomy site through an implant surgical guide. This technique can be particularly advantageous when the surgical guide restricts access for direct irrigation of the osteotomy site.

Using sequence clustering to identify clinically relevant subphenotypes in patients with COVID-19 admitted to the intensive care unit.

Objective: The novel coronavirus disease 2019 (COVID-19) has heterogenous clinical courses, indicating that there might be distinct subphenotypes in critically ill patients. Although prior research has identified these subphenotypes, the temporal pattern of multiple clinical features has not been considered in cluster models. We aimed to identify temporal subphenotypes in critically ill patients with COVID-19 using a novel sequence cluster analysis and associate them with clinically relevant outcomes.

EVIDENCE IS INSUFFICIENT WITH THE ASSOCIATION BETWEEN CANTILEVER TO ANTERIOR-POSTERIOR RATIO AND CLINICAL OUTCOMES OF FIXED IMPLANT-SUPPORTED FULL-ARCH PROSTHESIS.

Article Title And Bibliographic Information: Walter L, Greenstein G. Utility of measuring anterior-posterior spread to determine distal cantilever length off a fixed implant-supported full-arch prosthesis: A review of the literature. J Am Dent Assoc.

A Computational Method for Learning Disease Trajectories From Partially Observable EHR Data.

Diseases can show different courses of progression even when patients share the same risk factors. Recent studies have revealed that the use of trajectories, the order in which diseases manifest throughout life, can be predictive of the course of progression. In this study, we propose a novel computational method for learning disease trajectories from EHR data.

Open Proximal Contact with Implant-Supported Fixed Prostheses Compared with Tooth-Supported Fixed Prostheses: A Systematic Review and Meta-analysis.

Purpose: To investigate the odds of developing open proximal contact (OPC) between implant-supported fixed prostheses and adjacent teeth compared with that between tooth-supported fixed prostheses and adjacent teeth.

Materials And Methods: A search was conducted in the Ovid MEDLINE, Embase, and Web of Science databases for clinical studies on OPC developed with implant-supported prostheses or tooth-supported prostheses. A meta-analysis was performed using statistical software to estimate the odds of developing OPC with implant-supported prostheses compared with tooth-supported prostheses, with a 95% confidence interval (CI).

Incremental Effect of Aging on Obesity-Related Incident Chronic Kidney Disease in the Korean General Population.

Objectives: Obesity may increase the risk of kidney function decline. However, few studies have addressed how age modifies obesity-associated risk of chronic kidney disease (CKD) in the Asian general population.

Design: A community-based prospective cohort study.

Loss of nonvital abutment teeth for removable partial dentures: a systematic review and meta-analysis.

Objective: To analyze the loss of nonvital abutment teeth compared to vital abutment teeth supporting removable partial dentures (RPDs).

Method And Materials: An electronic search was conducted in the Ovid MEDLINE, Embase, and Web of Science databases, and supplemented by a manual search. The search was done to identify clinical studies reporting the loss of nonvital abutment teeth compared to vital abutment teeth for RPDs.

Bone loss in the anterior edentulous maxilla opposing two-implant-supported overdentures vs complete dentures: a systematic review and meta-analysis.

Objective: To investigate bone loss in the anterior edentulous maxilla restored with maxillary complete dentures and opposed by mandibular two-implant-supported overdentures (2-IODs) or complete dentures.

Method And Materials: A systematic search was conducted using the Ovid MEDLINE, Embase, Web of Science, CINAHL, and Cochrane databases for studies investigating bone loss in the anterior edentulous maxilla with mandibular 2-IODs or complete dentures. Two reviewers assessed the eligibility of studies and risk of bias assessment was conducted according to the Newcastle-Ottawa Scale.

Cement Type (Adhesive vs. Conventional) May Not Affect Clinical Performance of Zirconia and Lithium Disilicate Tooth-Supported Crowns.

Article Title And Bibliographic Information: Effect of cement type on the clinical performance and complications of zirconia and lithium disilicate tooth-supported crowns: A systematic review. Report of the Committee on Research in Fixed Prosthodontics of the American Academy of Fixed Prosthodontics. Maroulakos G, Thompson GA, Kontogiorgos ED.

Digital Workflow for Retrofitting a Surveyed Crown Using a Removable Partial Denture as an Antagonist.

Digital workflow expedites the procedure of retrofitting a surveyed crown against an existing removable partial denture (RPD). This article describes a simple and straightforward technique of digital workflow where an existing RPD is scanned as an antagonist to design the rest seat, guide plane, and height of contour of a surveyed crown.