Publications by authors named "Won-Soo Lee"

Background: Alopecia areata (AA) is a chronic autoimmune disease that leads to a high psychiatric, economic and systemic disease burden. A comprehensive understanding of AA epidemiology is essential for evaluating healthcare source utilization; however, a systematic approach to summarizing epidemiological data on AA is lacking.

Objectives: To investigate systematically the global, regional and national incidence and prevalence of AA.

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Background: Male androgenetic alopecia (MAGA) is often accompanied by female pattern hair loss (FPHL). However, the risk factors related to MAGA with FPHL are unclear.

Objective: To investigate demographic and laboratory factors related to MAGA with FPHL.

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Importance: Multiple cases of autoimmune and autoinflammatory diseases after COVID-19 have been reported. However, their incidences and risks have rarely been quantified.

Objective: To investigate the incidences and risks of autoimmune and autoinflammatory connective tissue disorders after COVID-19.

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Article Synopsis
  • Patients with lichen planopilaris (LPP) are at an increased risk of developing several comorbid diseases, including systemic lupus erythematosus, psoriasis, and rheumatoid arthritis, according to a nationwide study in Korea.
  • The research analyzed data from over 2,000 LPP patients and found they had higher incident rates of several conditions, as well as a higher mortality rate compared to matched controls, although the latter risk was not significant after adjusting for other health factors.
  • The study highlights the importance of regular monitoring and comprehensive care for patients diagnosed with LPP to better manage these associated health risks.
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Importance: Alopecia areata (AA) is associated with diverse autoimmune and psychiatric disorders. However, an investigation on the long-term outcomes for offspring born to mothers diagnosed with AA is lacking.

Objective: To investigate the risks for autoimmune, inflammatory, atopic, thyroid, and psychiatric outcomes of offspring born to mothers with AA.

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Background: Pediatric alopecia areata (AA) can affect the quality of life (QoL) of patients and their family members. Research on the QoL and burden on family members in pediatric AA is limited.

Objective: This nationwide multicenter questionnaire study described the QoL and burden of the family members of patients with pediatric AA.

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Article Synopsis
  • - The study aimed to determine how hair regrowth patterns in alopecia areata (AA) patches, classified as diffuse, irregular, marginal, and targetoid using the DIMT system, are influenced by treatment type and patch size.
  • - A retrospective analysis of 152 AA patches showed significant relationships: larger patches (>2 cm) were associated with diffuse and targetoid regrowth patterns, while the irregular pattern correlated strongly with triamcinolone acetonide treatment.
  • - The findings suggest that both the size of the patches and the type of treatment have a notable impact on different hair regrowth patterns in individuals with alopecia areata.
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Background: (CZ) belongs to the genus Chrysanthemum, also known as 'Gu-Jeol-Cho' in Korea. CZ has been used as herbal remedy to manage cough, hypertensive disorders, pharyngitis, bronchitis, gastroenteritis, pneumonia, bladder diseases and common cold. However, its effect on hair growth has not been documented.

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Importance: A recent expert consensus exercise emphasized the importance of developing a global network of patient registries for alopecia areata to redress the paucity of comparable, real-world data regarding the effectiveness and safety of existing and emerging therapies for alopecia areata.

Objective: To generate core domains and domain items for a global network of alopecia areata patient registries.

Evidence Review: Sixty-six participants, representing physicians, patient organizations, scientists, the pharmaceutical industry, and pharmacoeconomic experts, participated in a 3-round eDelphi process, culminating in a face-to-face meeting at the World Congress of Dermatology, Milan, Italy, June 14, 2019.

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