Effects of abutment screw preload in two implant connection systems: A 3D finite element study.

Statement Of Problem: Finite element analysis (FEA) has been used to evaluate the biomechanical behaviors of dental implants. However, in some FEA studies, the influence of the preload condition has been omitted to simplify the analysis. This might affect the results of biomechanical analysis significantly.

Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype.

Gastric cancer is a heterogeneous cancer, making treatment responses difficult to predict. Here we show that we identify two distinct molecular subtypes, mesenchymal phenotype (MP) and epithelial phenotype (EP), by analyzing genomic and proteomic data. Molecularly, MP subtype tumors show high genomic integrity characterized by low mutation rates and microsatellite stability, whereas EP subtype tumors show low genomic integrity.