Designing few-layered graphitic carbons with atomic-sized cobalt hydroxide by harnessing hollow metal-organic frameworks.

Graphitic carbon exhibits distinctive characteristics that can be modulated by varying the number of carbon layers. Here, we developed a method to control the growth of graphitic carbon layers through pyrolysis of zeolitic imidazolate frameworks (ZIFs). The key is to pyrolyze hollow-structured ZIF-8 containing Co ions to simultaneously obtain an amorphous carbon source for graphitic carbons and Co metal nanoparticles for catalyzing graphitization of amorphous carbons.

A hydrogen radical pathway for efficacious electrochemical nitrate reduction to ammonia over an Fe-polyoxometalate/Cu electrocatalyst.

Electrochemical nitrate (NO) reduction to ammonia (NH), which is a high value-added chemical or high-energy density carrier in many applications, could become a key process overcoming the disadvantages of the Haber-Bosch process; however, current electrocatalysts have severe drawbacks in terms of activity, selectivity, and stability. Here, we report the hydrogen radical (H*) pathway as a solution to overcome this challenge, as demonstrated by efficacious electrochemical NO reduction to NH over the Fe-polyoxometalate (Fe-POM)/Cu hybrid electrocatalyst. Fe-POM, composed of Preyssler anions ([NaPWO]) and Fe cations, facilitates efficient H* generation HO + e → H* + OH, and H* transfer to the Cu sites of the Fe-POM/Cu catalyst enables selective NO reduction to NH.

3D nitrogen-doped carbon frameworks with hierarchical pores and graphitic carbon channels for high-performance hybrid energy storages.

In principle, hybrid energy storages can utilize the advantages of capacitor-type cathodes and battery-type anodes, but their cathode and anode materials still cannot realize a high energy density, fast rechargeable capability, and long-cycle stability. Herein, we report a strategy to synthesize cathode and anode materials as a solution to overcome this challenge. Firstly, 3D nitrogen-doped hierarchical porous graphitic carbon (NHPGC) frameworks were synthesized as cathode materials using Co-Zn mixed metal-organic frameworks (MOFs).

Coiled Conformation Hollow Carbon Nanosphere Cathode and Anode for High Energy Density and Ultrafast Chargeable Hybrid Energy Storage.

Lithium-ion batteries and pseudocapacitors are nowadays popular electrochemical energy storage for many applications, but their cathodes and anodes are still limited to accommodate rich redox ions not only for high energy density but also sluggish ion diffusivity and poor electron conductivity, hindering fast recharge. Here, we report a strategy to realize high-capacity/high-rate cathode and anode as a solution to this challenge. Multiporous conductive hollow carbon (HC) nanospheres with microporous shells for high capacity and hollow cores/mesoporous shells for rapid ion transfer are synthesized as cathode materials using quinoid:benzenoid (Q:B) unit resins of coiled conformation, leading to ∼5-fold higher capacities than benzenoid:benzenoid resins of linear conformation.

Comparing Internal and Interparticle Space Effects of Metal-Organic Frameworks on Polysulfide Migration in Lithium-Sulfur Batteries.

One of the critical issues hindering the commercialization of lithium-sulfur (Li-S) batteries is the dissolution and migration of soluble polysulfides in electrolyte, which is called the 'shuttle effect'. To address this issue, previous studies have focused on separators featuring specific chemical affinities or physical confinement by porous coating materials. However, there have been no studies on the complex effects of the simultaneous presence of the internal and interparticle spaces of porous materials in Li-S batteries.

Metal-Organic Fragments with Adhesive Excipient and Their Utilization to Stabilize Multimetallic Electrocatalysts for High Activity and Robust Durability in Oxygen Evolution Reaction.

Multimetallic electrocatalysts have shown great potential to improve electrocatalytic performance, but their deteriorations in activity and durability are yet to be overcome. Here, metal-organic fragments with adhesive excipient to realize high activity with good durability in oxygen evolution reaction (OER) are developed. First, a leaf-like zeolitic-imidazolate framework (ZIF-L) is synthesized.

Immunosuppressant treatment for IgG4-related sclerosing cholangitis: A case report.

Background: Immunoglobulin G4-related disease (IgG4-RD) is a multi-system fibroin-flammatory disorder that can involve any organ, including the salivary glands, pancreas, and biliary tree. Treatment of immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is similar to that for IgG4-RD, but progression is irreversible in some cases. We present a case of IgG4-SC in which an immuno-suppressant induced marked clinical and radiologic improvement.

Comparison of the efficacy and safety of CELBESTA® versus CELEBREX® in patients with rheumatoid arthritis: a 6-week, multicenter, double-blind, double-dummy, active-controlled, randomized, parallel-group, non-inferiority phase 4 clinical trial.

Objectives: Celecoxib is a selective cyclooxygenase (COX)-2 inhibitor that is commonly used to reduce the incidence of gastrointestinal (GI) complications in patients with rheumatoid arthritis (RA). CELBESTA® is a generic equivalent to CELEBREX®, a celecoxib preparation. This study compared the efficacy and safety of CELBESTA® and CELEBREX® in patients with RA.

Autogenous Production and Stabilization of Highly Loaded Sub-Nanometric Particles within Multishell Hollow Metal-Organic Frameworks and Their Utilization for High Performance in Li-O Batteries.

Sub-nanometric particles (SNPs) of atomic cluster sizes have shown great promise in many fields such as full atom-to-atom utilization, but their precise production and stabilization at high mass loadings remain a great challenge. As a solution to overcome this challenge, a strategy allowing synthesis and preservation of SNPs at high mass loadings within multishell hollow metal-organic frameworks (MOFs) is demonstrated. First, alternating water-decomposable and water-stable MOFs are stacked in succession to build multilayer MOFs.

The angiography-guided spot versus entire stenting in patients with long coronary lesions trial: Study design and rationale for a randomized controlled trial protocol.

Background: : Long-stenting, even with a second-generation drug-eluting stent (DES), is an independent predictor of restenosis and stent thrombosis in patients with long coronary lesions. Spot-stenting, i.e.

Cobalt-Phosphate Catalysts with Reduced Bivalent Co-Ion States and Doped Nitrogen Atoms Playing as Active Sites for Facile Adsorption, Fast Charge Transfer, and Robust Stability in Photoelectrochemical Water Oxidation.

A cobalt-phosphate (Co-Pi) catalyst having octahedral CoO molecular units as reaction sites is a key component in photoelectrochemical (PEC) water oxidation systems, but its limited adsorption sites for oxygen-evolving intermediates (*OH, *OOH), slow charge transfer rates, and fast degradation of reaction sites are yet to be overcome. Here, we report that Co-Pi nanoparticles with low-coordinate Co ions and doped nitrogen atoms could be decorated on hematite nanorod arrays to form N-CoPi/hematite composites. Moreover, the local atomic configuration and bond distance studies show that trivalent Co states are partially reduced through nitrogen radicals in the plasma to low-coordinate bivalent Co states playing as the facile adsorption sites of oxygen-evolving intermediates due to the decreased activation barrier for water oxidation.

Ultrafine Metallic Nickel Domains and Reduced Molybdenum States Improve Oxygen Evolution Reaction of NiFeMo Electrocatalysts.

An electrocatalyst for oxygen evolution reaction (OER) is essential in the realization of renewable energy conversion technologies, but its large overpotential, slow charge transfer, and degradation of surface reaction sites are yet to be overcome. Here, it is found that the metallic nickel domains and high-valence reduced molybdenum ions of NiFeMo electrocatalysts grown on a 3D conductive and porous electrode without using binders enable ultrahigh performance in OER. High resolution-transmission electron microscope and extended X-ray absorption fine structure analyses show that metallic nickel domains with Ni-Ni bonds are generated on the catalyst surface via a dry synthesis using nitrogen plasma.

Effects of weighted baseball throwing during warm-up on ball velocity and upper extremity muscle activation in baseball pitchers.

The objective of this study was to investigate the changes in the muscle activation of high school and college baseball pitchers during throwing of the ball with maximum effort (TBME) using a regular baseball (RB) subsequent to using a light baseball (LB), RB, and overweight baseball (OB) during warm-up (WU) and the resulting changes in the pitch velocity. The study aimed to use the findings in providing basic data for a training program designed to increase the pitch velocity of baseball pitchers. The study population consisted of 12 high school and college baseball players.

Effects of virtual reality intervention on upper limb motor function and activity of daily living in patients with lesions in different regions of the brain.

[Purpose] This study aimed to investigate whether a virtual reality (VR) intervention has an influence in improving the motor function and activities of daily living (ADLs) in patients with lesions in different regions of the brain. [Subjects and Methods] Eleven subjects with hemiplegic stroke were recruited in this study, which was conducted from January to February, 2017. They received a VR intervention once a day for 30 min, 5 times a week for 4 weeks.

Effects of repeated vibratory stimulation of wrist and elbow flexors on hand dexterity, strength, and sensory function in patients with chronic stroke: a pilot study.

[Purpose] The aim of this study was to investigate the effects of repeated vibratory stimulation to muscles related to hand functions on dexterity, strength, and sensory function in patients with chronic stroke. [Subjects and Methods] A total of 10 stroke patients with hemiplegia participated in this study. They were divided into two groups: a) Experimental and b) Control, with five randomly selected subjects for each group.

Nitrogen-Doped Carbon Nanocoil Array Integrated on Carbon Nanofiber Paper for Supercapacitor Electrodes.

Integrating a nanostructured carbon array on a conductive substrate remains a challenging task that presently relies primarily on high-vacuum deposition technology. To overcome the problems associated with current vacuum techniques, we demonstrate the formation of an N-doped carbon array by pyrolysis of a polymer array that was electrochemically grown on carbon fiber paper. The resulting carbon array was investigated for use as a supercapacitor electrode.

Clinical Relevance of Poststent Fractional Flow Reserve After Drug-Eluting Stent Implantation.

Background: The prognostic value of poststent fractional flow reserve (FFR) has not been clearly defined in patients with drug-eluting stent (DES) implantation. This study sought to evaluate the association between FFR and clinical outcomes after DES implantation with intravascular ultrasound (IVUS) assistance.

Methods: A total of 115 lesions (107 patients) with FFR measurement after IVUS-assisted DES implantation were enrolled.

A study on the effect of self bedside exercise program on resilience and activities of daily living for patients with hemiplegia.

The purpose of this study was to design a repeatable universal rehabilitation program in which patients with hemiplegia can participate voluntarily, complementing physical and occupational therapies to increase voluntary exercise practice rate. Also, this study attempted to identify the relationship between psychological resilience due to the implementation of self-bedside exercise and functional recovery of activity of daily living (ADL). 12 patients with hemiplegia voluntarily participated in 8 weeks of self-bedside exercise 5 times a day and more than 5 days a week.

Patent foramen ovale and asymptomatic brain lesions in military fighter pilots.

Background And Purpose: Previous studies have reported higher incidence of white matter lesions (WMLs) in military pilots. The anti-gravity straining maneuver, which fighter military pilots perform numerously during a flight is identical to the valsalva maneuver. We sought to investigate the prevalence of right-to-left shunt (RLS) associated with WMLs in military pilots.

Extremely delayed brain metastasis from renal cell carcinoma.

Brain metastasis occurs in 3.9-24% of patients with renal cell carcinoma (RCC), with an average interval from nephrectomy to brain metastasis of 1 to 3 years. A few cases have been reported where brain metastasis occurred after a delay of more than 10 years from the initial onset of renal cell carcinoma.