Comparison of two prediction equations with radionuclide glomerular filtration rate: validation in routine use.

Background: Recent guidelines recommend automatic reporting of estimated glomerular filtration rate (eGFR) using the abbreviated Modification of Diet in Renal Disease (MDRD) equation with every request for plasma creatinine. We evaluated the performance of the MDRD and Cockcroft-Gault equations in routine use compared with a radionuclide GFR method.

Method: Data collected on 601 patients aged 16-85 years who had undergone radionuclide GFR and eGFR was calculated using both equations for each patient.