Background And Aims: Multiple clinical trials have demonstrated the efficacy and safety of tenofovir disoproxil fumarate (TDF) in chronic hepatitis B (CHB). However, long-term efficacy and safety data for TDF in real-life clinical practice are limited.
Methods: Prospective German field practice study in CHB-mono-infected patients.
Aviat Space Environ Med
November 2007
Introduction: Previously, we have shown that naïve subjects produce exaggerated isometric forces when exposed to increased acceleration (+Gz) for the first time. The present study investigates whether +G,-experienced PA-200 Tornado pilots show similar deficits.
Methods: Experiments were conducted in the stationary (+1 Gz) or rotating (+3 Gz) gondola of a human-rated centrifuge.
Aviat Space Environ Med
October 2007
Background: We have shown before that novice human subjects produce exaggerated isometric forces when exposed to three times normal terrestrial acceleration (+3 Gz), and that this deficit is compensated by intensive training in +3 Gz. We now investigate whether training in normal terrestrial gravity (normal G) is also effective. We further examine whether subjects in +3 Gz produce not only exaggerated forces, but also exaggerated hand displacements.
View Article and Find Full Text PDFAviat Space Environ Med
June 2006
Background: In our earlier work, we have shown that human subjects produce exaggerated isometric forces when exposed to three times terrestrial gravity (+3 Gz). In the present work, we investigated whether prolonged practice under +3 Gz reduces this deficit, and whether it affects the cognitive costs of force production.
Methods: There were 24 young male student volunteers who produced forces without visual feedback of prescribed directions and magnitudes with their dominant hand, and used their other hand for a four-choice reaction-time task.